Evidence map›Paper›PMID 40629326›Full record

ArticleBMC medicine2025

Obsessive-compulsive disorder in the World Mental Health surveys.

Dan J Stein, Ayelet Meron Ruscio, Yasmin Altwaijri, Wai Tat Chiu, Nancy A Sampson, Sergio Aguilar-Gaxiola, Ali Al-Hamzawi, Jordi Alonso, Stephanie Chardoul, Oye Gureje and 12 more

Abstract read
In one paragraph

Article in BMC medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. A Gut-Brain Axis Underlying Succinate-Associated Compulsive-Like Behavior.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
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  12. The Prevalence of Tic Disorders in Poland: Regional and Sex Differences.Tremor and other hyperkinetic movements (New York, N.Y.) · 2026
    Article
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  15. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

22 authors.

Dan J Stein *SAMRC Unit On Risk & Resilience in Mental Disorders, Dept of Psychiatry & Neuroscience Institute, University of Cape Town, Cape Town, South Africa. dan.stein@uct.ac.za.
Ayelet Meron Ruscio *Department of Psychology, University of Pennsylvania, Philadelphia, PA, USA.
Yasmin AltwaijriBiostatistics, Epidemiology and Scientific Computing Department, King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia.
Wai Tat ChiuDepartment of Health Care Policy, Harvard Medical School, Boston, MA, USA.
Nancy A SampsonDepartment of Health Care Policy, Harvard Medical School, Boston, MA, USA.
Sergio Aguilar-GaxiolaDepartment of Internal Medicine, Center for Reducing Health Disparities, UC Davis Health System, Sacramento, CA, USA.
Ali Al-HamzawiCollege of Medicine, University of Al-Qadisiya, Al Diwaniyah, Diwaniya Governorate, Iraq.
Jordi AlonsoHealth Services Research Unit, Hospital del Mar Medical Research Institute (IMIM), Barcelona, Spain.
Stephanie ChardoulSurvey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA.
Oye GurejeDepartment of Psychiatry, University College Hospital, Ibadan, Nigeria.
Chiyi HuShenzhen Institute of Mental Health & Shenzhen Kangning Hospital, Shenzhen, China.
Elie G KaramInstitute for Development, Research, Advocacy and Applied Care (IDRAAC), ResearchBeirut, Lebanon.
John J McGrathQueensland Centre for Mental Health Research, The Park Centre for Mental Health, Wacol, QLD, Australia.
Fernando Navarro-MateuUnidad de Docencia, Investigacion y Formación en Salud Mental (UDIF-SM), Servicio Murciano de Salud, Murcia Health Service, C/Lorca, nº 58. - El Palmar, Murcia, 30120, Spain.
Kate M ScottDepartment of Psychological Medicine, University of Otago, Dunedin, Otago, New Zealand.
Juan Carlos StagnaroDepartamento de Psiquiatría y Salud Mental, Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina.
Yolanda TorresCenter for Excellence On Research in Mental Health, CES University, Medellín, Colombia.
Cristian VladescuNational Institute for Health Services Management, Bucharest, Romania.
Jacek WciórkaDepartment of Psychiatry, Institute of Psychiatry and Neurology, Warsaw, Poland.
Miguel XavierNova Medical School, Nova University of Lisbon, Lisbon, Portugal.
Ronald C KesslerDepartment of Health Care Policy, Harvard Medical School, Boston, MA, USA.
World Mental Health Survey collaborators

Funding

Risk Factors for Psychopathology in the WHO WMH SurveysR01MH070884 · NIMH · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI KESSLER, RONALD C · 2005 to 2009
$6.0M
NIMH NIH HHS R01 MH070884
6 · The paper itself

Abstract

backgroundNational surveys have suggested that obsessive-compulsive disorder (OCD) is a prevalent and impairing condition. However, there are few cross-national data on OCD, with data particularly scarce in low- and middle-income countries. Here we employ data from the World Mental Health surveys to characterize the onset, course, severity, and treatment of OCD across a range of countries in different geographic regions of the world.

methodsData came from general population surveys carried out in 10 countries (Argentina, Australia, Colombia, Iraq, Poland, People's Republic of China, Portugal, Romania, Saudi Arabia, Spain) using a consistent research protocol and interview. A total of 26,136 adults were assessed for OCD in face-to-face interviews and were included in the present analyses. We examined lifetime and 12-month prevalence as well as age of onset, persistence, severity, and treatment of DSM-IV OCD in six high-income countries (HICs) and four low- or middle-income countries (LMICs). We also investigated socio-demographic variables and temporally prior mental disorders as predictors of OCD onset, persistence, severity, and treatment.

resultsAcross the 10 countries surveyed, OCD has a combined lifetime prevalence of 4.1%. The 12-month prevalence (3.0%) is nearly as high, suggesting a highly persistent course of illness. Age of onset is early, with more than 80% of OCD cases beginning by early adulthood. Most OCD cases in the community are mild (47.0%) or very mild (27.5%), with a smaller percentage designated as moderate (22.9%) or severe (2.7%) by the Yale-Brown Obsessive-Compulsive Scale. Only 19.8% of respondents with OCD received any mental health treatment in the past year, with treatment rates much higher in HICs (40.5%) than LMICs (7.0%). Cross-nationally, OCD commonly emerges in adolescence or early adulthood against a backdrop of earlier-occurring mental disorders. With few exceptions (e.g., prior social phobia), the socio-demographic and psychopathological risk factors for OCD onset, persistence, severity, and treatment are distinct.

conclusionsThese cross-national data underscore clinical lessons regarding the importance of early diagnosis of OCD and comprehensive evaluation of comorbidity; draw attention to OCD as an undertreated disorder, particularly in LMIC contexts; and emphasize the public health significance of this often-overlooked condition.

Indexed as

Global HealthObsessive-Compulsive DisorderAdolescentAdultAge of OnsetFemaleHealth SurveysHumansMaleMiddle AgedPrevalenceSeverity of Illness IndexYoung AdultCommunity epidemiologyGlobal mental healthObsessive-compulsive disorderWorld Mental Health surveys

Identifiers

PMID40629326
PMCPMC12239380

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.