Evidence map›Paper›PMID 40629425›Full record

ReviewJournal of biomedical science2025

Chitosan-based formulations for therapeutic applications. A recent overview.

Weronika Gonciarz, Ewa Balcerczak, Marek Brzeziński, Agnieszka Jeleń, Agnieszka J Pietrzyk-Brzezińska, Vedha Hari B Narayanan, Magdalena Chmiela

Abstract readReview
In one paragraph

Review in Journal of biomedical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
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  6. Article
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  8. Review
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  14. Pickering Emulsion Stabilized by Chitosan-ModifiedPharmaceuticals (Basel, Switzerland) · 2026
    Article
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Weronika GonciarzDepartment of Immunology and Infectious Biology, Institute of Microbiology, Biotechnology, and Immunology, Faculty of Biology and Environmental Protection, University of Lodz, Banacha 12/16, 90-237, Lodz, Poland. weronika.gonciarz@biol.uni.lodz.pl.
Ewa BalcerczakDepartment of Pharmaceutical Biochemistry and Molecular Diagnostics, Medical University of Lodz, Muszynskiego 1, 90-151, Lodz, Poland.
Marek BrzezińskiCentre of Molecular and Macromolecular Studies, Polish Academy of Sciences, Sienkiewicza 112, 90-363, Lodz, Poland.
Agnieszka JeleńDepartment of Pharmaceutical Biochemistry and Molecular Diagnostics, Medical University of Lodz, Muszynskiego 1, 90-151, Lodz, Poland.
Agnieszka J Pietrzyk-BrzezińskaInstitute of Molecular and Industrial Biotechnology, Faculty of Biotechnology and Food Sciences, Lodz University of Technology, Stefanowskiego 2/22, 90-537, Lodz, Poland.
Vedha Hari B NarayananPharmaceutical Technology Laboratory, #214, ASK-II, School of Chemical and Biotechnology, SASTRA Deemed University, Thanjavur, 613401, Tamil Nadu, India.
Magdalena ChmielaDepartment of Immunology and Infectious Biology, Institute of Microbiology, Biotechnology, and Immunology, Faculty of Biology and Environmental Protection, University of Lodz, Banacha 12/16, 90-237, Lodz, Poland.

Funding

Narodowe Centrum Nauki 2022/47/D/NZ7/01097
6 · The paper itself

Abstract

Chitosan is a cationic natural polymer composed of glucosamine and N-acetylglucosamine residues that are held together by a glycosidic bond. Chitosan has many excellent properties, including physicochemical properties, i.e., stability in the natural environment, chelation of metal ions, high sorption properties, biological properties such as biocompatibility and biological activity, ecological properties resulting from biodegradability, and physiological properties, which include non-toxicity, and economic affordability, and is used in various biomedical and industrial applications. The presented article highlights recent developments in chitosan-based formulations for the treatment of bacteria, viruses, cancer, or gastroesophageal reflux disease. Moreover, chitosan-derived biomaterials can also be used in regenerative medicine or food packaging to prevent contamination by pathogenic microorganisms. In summary, this is a valuable compilation in this emerging field that focuses on the biomedical application of chitosan-based biomaterials.

Indexed as

Biocompatible MaterialsChitosanAnimalsHumansBiocompatible MaterialsChitosanBiomedical applicationsChitosanMicroparticlesNanoparticles

Identifiers

PMID40629425
PMCPMC12239286

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.