ReviewFrontiers in pharmacology2025
Advances in hydrogel-based materials for breast cancer bone metastasis: from targeted drug delivery to bone microenvironment remodeling.
Review in Frontiers in pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Breast cancer has become the most common malignant tumor in women around the world, and bones are the most common part of all metastatic breast cancers. Breast cancer bone metastasis (BCBM) is the main cause of death in patients with advanced breast cancer. It is still mainly clinically palliative treatment, with problems such as systemic toxicity, low target specificity, and insufficient bone repair. Therefore, there is an urgent need to develop new therapeutic strategies to overcome these challenges. This review summarizes recent advances and innovative applications of smart hydrogel-based delivery systems for breast cancer bone metastasis, highlighting their significant potential in gene delivery and immune microenvironment remodeling. Current limitations and future research directions are also discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.