ArticleFrontiers in nutrition2025
Underweight was associated with increased mortality in adults with latent tuberculosis infection.
Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Latent tuberculosis (TB) infection (LTBI) is a reservoir for active TB. Although body mass index (BMI) predicts LTBI progression and influences active TB outcomes, its association with mortality in LTBI patients remains unclear. We therefore investigated this relationship in a US cohort. Research methods & procedures: Data from the National Health and Nutrition Examination Survey 2011-2012 was utilized. Survival differences across BMI categories were assessed with Kaplan-Meier curves and multivariable Cox regression. The Restricted Cubic Spline (RCS) analysis modeled the nonlinear relationship between BMI and mortality risk. Results: Among 700 LTBI participants analyzed, multivariable Cox regression identified underweight individuals as having higher mortality risk than normalweight counterparts (adjusted HR = 2.77, 95% CI 1.06-7.22, Conclusion: In LTBI adults, underweight status independently predicted increased mortality risk, while overweight or obesity showed no association. RCS analysis confirmed a U-shaped BMI-mortality relationship with optimal survival at 27.3 kg/m
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.