ArticleTransboundary and emerging diseases2025
Replication and Virulence in Cattle of the First Lumpy Skin Disease Virus Isolated in Xinjiang, China (2019).
Article in Transboundary and emerging diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Development of a Duplex TaqMan-MGB qPCR Assay for Differential Detection of Chinese Epidemic Lumpy Skin Disease Virus Strains and Goatpox Virus.Animals : an open access journal from MDPI · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Before 2012, lumpy skin disease (LSD) was primarily confined to African countries. However, it rapidly spread to the Middle East and Southeast Europe, reaching the Balkans, the Caucasus, and the Russian Federation by 2015. The first confirmed case in China was reported on August 10, 2019, in Yili, Xinjiang, and on August 26, the Chinese government officially notified the World Organization for Animal Health (WOAH) of the outbreak. In this study, we isolated a LSD virus (LSDV) strain from a severely affected cattle skin sample collected in the Yili region of Xinjiang and designated it as strain Xinjiang/2019. Next-generation sequencing (NGS) analysis revealed that strain Xinjiang/2019 shared the highest similarity with the LSDV/Russia/Saratov/2017 strain based on full-length LSDV sequences available in NCBI. Phylogenetic analysis revealed that the Xinjiang/2019 isolate clustered with strains from China, Vietnam, Thailand, and Indonesia, forming a distinct phylogenetic branch. Recombination analysis further indicated that Xinjiang/2019 is predominantly a recombinant strain, derived from South African and European strains. To assess pathogenicity, cattle were infected with strain Xinjiang/2019 via intravenous (Group I) or intradermal (Group II) injection. In Group I, four out of five animals developed typical LSD symptoms, including fever (day 7), secondary nodules (day 8), rhinitis, conjunctivitis, and lymph node enlargement. Group II showed viremia by day 5 with milder symptoms. These findings indicate that strain Xinjiang/2019 is a virulent strain responsible for the first LSD outbreak in China.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.