ArticleFrontiers in pediatrics2025
Global, regional, and national burden of sudden infant death syndrome, 1990-2021: a comprehensive analysis of GBD 2021 data with insights into the impact during the COVID-19 pandemic.
Article in Frontiers in pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Unmasking immunodeficiency in sudden infant deaths: no evidence of hidden immune disorders.Frontiers in immunology · 2026Article
- Serotonergic receptor binding in the brainstem in the Sudden Infant Death Syndrome in a high-risk population.PloS one · 2025Article
- Magnitude of Premature Mortality From Sudden Infant Death Syndrome in Ethiopia, From 1990 to 2023.Sage open pediatricsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Sudden infant death syndrome (SIDS) remains a leading cause of infant mortality globally. Although the global burden has generally declined over recent decades, the COVID-19 pandemic may have influenced these trends. This study investigates whether the global SIDS burden has changed, particularly during the COVID-19 pandemic. Methods: Data from the Global Burden of Disease (GBD) 2021 study were analyzed to estimate SIDS mortality and disability-adjusted life years (DALYs) globally, regionally, and nationally. Rates were stratified by sex, age group, socio-demographic index (SDI), and health system level. Projections were made using the Bayesian Age-Period-Cohort model and the the autoregressive integrated moving average (ARIMA) model. Results: In 2021, global SIDS deaths totaled 30,608, with a mortality rate of 24.16 per 100,000 infants (95% UI, 14.06-32.44). Global DALYs were 2,746,174, at a rate of 2,167.56 per 100,000 infants (95% UI, 1,261.44-2,909.59). Mortality and DALYs rates decreased by 59% from 1990 to 2021, with marked regional differences. Regions with Low SDI and Minimal health systems, particularly Sub-Saharan Africa, had the highest burden, while higher SDI and advanced health system regions reported significant declines. Male infants aged 1-5 months showed higher rates than females. Despite a global decline during the pandemic, temporary increases occurred in countries including China, the Russian Federation, and Monaco. Projections suggest continued declines, predicting a mortality rate of 16.86 per 100,000 infants and DALYs rate of 1,400.41 per 100,000 infants by 2035. Conclusions: The global SIDS burden has consistently declined since 1990, including during COVID-19, yet significant regional disparities remain. Enhanced healthcare interventions and targeted public health initiatives are crucial, particularly in regions with Low SDI and Minimal health system resources.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.