Evidence map›Paper›PMID 40631039›Full record

ArticleJTCVS open2025

Outcomes of prolonged support on surgically implanted microaxial left ventricular assist devices for refractory cardiogenic shock.

Iris Feng, Gabriel Dardik, Yuji Kaku, Yanling Zhao, Henry Del Carmen, John DePaolo, Marisa Cevasco, Mauer Biscotti, Joyce W Wald, Justin A Fried and 1 more

Abstract read
In one paragraph

Article in JTCVS open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Iris FengDivision of Cardiothoracic and Vascular Surgery, Department of Surgery, Columbia University Irving Medical Center, New York, NY.
Gabriel DardikDivision of Cardiothoracic and Vascular Surgery, Department of Surgery, Columbia University Irving Medical Center, New York, NY.
Yuji KakuDivision of Cardiothoracic and Vascular Surgery, Department of Surgery, Columbia University Irving Medical Center, New York, NY.
Yanling ZhaoDivision of Cardiothoracic and Vascular Surgery, Department of Surgery, Columbia University Irving Medical Center, New York, NY.
Henry Del CarmenDivision of Cardiac Surgery, Department of Surgery, Hospital of the University of Pennsylvania, Philadelphia, Pa.
John DePaoloDivision of Cardiac Surgery, Department of Surgery, Hospital of the University of Pennsylvania, Philadelphia, Pa.
Marisa CevascoDivision of Cardiac Surgery, Department of Surgery, Hospital of the University of Pennsylvania, Philadelphia, Pa.
Mauer BiscottiDivision of Cardiac Surgery, Department of Surgery, Hospital of the University of Pennsylvania, Philadelphia, Pa.
Joyce W WaldDivision of Cardiology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pa.
Justin A FriedDivision of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY.
Koji TakedaDivision of Cardiothoracic and Vascular Surgery, Department of Surgery, Columbia University Irving Medical Center, New York, NY.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The US Food and Drug Administration approved the use of Impella 5.5 (Abiomed) for mechanical circulatory support for up to 14 days, but many patients require longer duration of support. This study sought to compare outcomes of standard versus prolonged Impella 5.5 support. Methods: A retrospective review of 257 patients implanted with the Impella 5.5 device between 2020 and 2024 for cardiogenic shock at 2 high-volume institutions was conducted. Patients were stratified by standard (≤14 days) (n = 143) versus prolonged (>14 days) (n = 114) device support. Results: At baseline, the etiology of shock was more likely to be acute decompensated heart failure (74.6% vs 52.4%; Conclusions: Extended Impella 5.5 device support beyond 14 days was not associated with increased incidence of mortality, major bleeding, or stroke in our study, and may be effective for patients requiring extended ventricular assist device support as bridge to heart transplant.

Indexed as

bridge to transplantcardiogenic shockImpellamechanical circulatory supportventricular assist device

Identifiers

PMID40631039
PMCPMC12230556

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.