ArticlebioRxiv : the preprint server for biology2025
High-performance genetically-encoded green and red fluorescent biosensors for pyruvate.
Shosei Imai, Saaya Hario, Carl Suerte, Issei Yamaguchi, Kenryo Sakoi, Adam Thuen, Brekken Meznarich, Mikhail Drobizhev, Takuya Terai, Kei Takahashi-Yamashiro and 1 more
Abstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
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4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
11 authors.
Shosei ImaiDepartment of Chemistry, School of Science, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan.ORCID 0000-0003-0388-4764 Saaya HarioDepartment of Chemistry, School of Science, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan.ORCID 0000-0003-0127-3142 Carl SuerteDepartment of Chemistry, School of Science, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan.
Issei YamaguchiDepartment of Chemistry, School of Science, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan.
Kenryo SakoiDepartment of Chemistry, School of Science, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan.
Adam ThuenDepartment of Microbiology and Cell Biology, Montana State University, Bozeman, Montana 59717, United States.
Brekken MeznarichDepartment of Microbiology and Cell Biology, Montana State University, Bozeman, Montana 59717, United States.
Mikhail DrobizhevDepartment of Microbiology and Cell Biology, Montana State University, Bozeman, Montana 59717, United States.
Takuya TeraiDepartment of Chemistry, School of Science, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan.ORCID 0000-0002-3425-3589 Kei Takahashi-YamashiroDepartment of Chemistry, School of Science, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan.ORCID 0000-0002-7925-6636 Robert E CampbellDepartment of Chemistry, School of Science, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan.ORCID 0000-0003-0604-092X Funding
Resource for Multiphoton Characterization of Genetically-Encoded ProbesU24NS109107 · NINDS · MONTANA STATE UNIVERSITY - BOZEMAN · PI Mikhail Drobizhev · 2018 to 2026
$2.2MNINDS NIH HHS U24 NS109107
6 · The paper itselfAbstract
Pyruvate is the end-product of glycolysis and a central metabolite involved in many biochemical pathways. However, a lack of high-performance (i.e., Δ
Identifiers
PMID40631294
PMCPMC12236856
What Socratic holds
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