Evidence map›Paper›PMID 40632797›Full record

ArticleDiabetic medicine : a journal of the British Diabetic Association2025

Partial starch substitution with resistant starch lowers postprandial glucose and glycaemic variability in people with type 2 diabetes.

Sineaid M Collins, M Bernadette Egan, Martin B Whyte, M Denise Robertson

Abstract read
In one paragraph

Article in Diabetic medicine : a journal of the British Diabetic Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sineaid M CollinsFaculty of Health and Medical Sciences, University of Surrey, Guildford, UK.ORCID https://orcid.org/0000-0003-2861-8534
M Bernadette EganFaculty of Health and Medical Sciences, University of Surrey, Guildford, UK.
Martin B WhyteFaculty of Health and Medical Sciences, University of Surrey, Guildford, UK.ORCID https://orcid.org/0000-0002-2897-2026
M Denise RobertsonFaculty of Health and Medical Sciences, University of Surrey, Guildford, UK.

Funding

Diabetes UK
6 · The paper itself

Abstract

aimsApproximately 40% of the caloric intake of the UK diet consists of starch. Most of which is readily digestible, thereby raising blood glucose. However, resistant starch (RS) evades metabolism in the small intestine, and in healthy adults, partial substitution of the diet with RS lowers postprandial glycaemia. The effect of RS in adults with type 2 diabetes is unknown.

methodsWe investigated the effect of substituting ~15% of dietary starch with RS on glycaemic measures in adults with type 2 diabetes in a controlled but free-living setting. This was a single-blinded, crossover design, comparing 4-day RS and control diets. Proportions of resistant and digestible starch in identical food products were the only difference. IPro™2 continuous glucose monitors captured glycaemic excursions and glycaemic variability.

resultsTwenty adults with type 2 diabetes, HbA

conclusionSubstituting a proportion of starch with RS lowers blood glucose without changing the sensory attributes of foods significantly. There is potential to develop a functional diet for adults with type 2 diabetes to aid glycaemic control.

Indexed as

Blood GlucoseDiabetes Mellitus, Type 2Dietary CarbohydratesResistant StarchStarchAdultAgedCross-Over StudiesFemaleGlycated HemoglobinGlycemic ControlHumansMaleMiddle AgedPostprandial PeriodSingle-Blind MethodBlood GlucoseDietary CarbohydratesGlycated HemoglobinResistant StarchStarchcardio‐vascular diseasefunctional foodsHbA1cpostprandial glucoseresistant starchstarch substitutiontype 2 diabetes

Identifiers

PMID40632797
PMCPMC12352712

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.