ArticleDevelopmental cell2025
The histone variant H3.14 is an early player in the abiotic stress response of Arabidopsis.
Article in Developmental cell, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Replication-independent eviction of the histone variant H2B.8 reveals chromatin reprogramming during seed imbibition.Nature communications · 2026Article
- Research Progress on Histone Modification Regulation Mechanisms and Breeding Applications in Plant Abiotic Stress Responses.Plants (Basel, Switzerland) · 2026Review
- Transcriptome and eQTL analysis reveal the novel molecular mechanism underlying salt tolerance in the phytochrome B mutant.Plant cell reports · 2026Article
- Histone variant H2A.X represses deposition of active H3K4me3 marks and restricts H2A.W incorporation.Nucleic acids research · 2026Article
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Authors and funding
6 authors.
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Abstract
The combinatorial changes in DNA methylation, post-translational histone modifications, and histone variants underlie the complexity of chromatin structure and function. In the case of histone H3, apart from the canonical H3.1 and the variant H3.3, highly conserved in eukaryotes, there are additional members associated with unique developmental features, some of which have an unknown function. Here, we have investigated one of these, H3.14, a novel Arabidopsis H3 variant rapidly and transiently induced upon abiotic stress in a subset of responsive cells located in the root transition zone. Chromatin immunoprecipitation sequencing (ChIP-seq) and RNA sequencing (RNA-seq) data showed that H3.14 exhibits differential binding patterns in repressed genes involved in cell growth and in activated genes involved in the stress response. This dual role, further supported by genetic and cell biology data, led us to conclude that H3.14 is specifically tailored for the transcriptional rewiring during the early abiotic stress response.
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