ArticleScientific data2025
Age- and Sex-Specific Cerebral Blood Flow Atlases for Healthy Brain Across the Lifespan.
Article in Scientific data, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed.
- Denoising of ASL Data Using Deep Learning Priors Generated From Distribution Remapping.Magnetic resonance in medicine · 2026Article
- Reduced microvascular coverage links a hypoxia-associated niche to microglial autophagic dysfunction in Parkinson's disease.Acta neuropathologica communications · 2026Article
- An MRI Atlas of Regional Brain Vulnerability to Metastatic Disease.medRxiv : the preprint server for health sciences · 2026Article
- Age- and Sex-Specific Cerebral Blood Flow Atlases for Healthy Brain Across the Lifespan.Scientific data · 2025Article
- Individualized cholinergic pathway degeneration in Alzheimer's disease characterized by normative modeling.Alzheimer's & dementia (Amsterdam, Netherlands)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Cerebral blood flow (CBF) is a crucial biological marker providing valuable insights into the developmental and aging processes of the central nervous system. A comprehensive understanding of the age- and sex-specific distribution of CBF in healthy populations is essential for distinguishing between pathological changes and those associated with normal aging. This study introduces a collection of age- and sex-specific CBF atlases across the lifespan (7-93 years old), derived from a large data size (N = 1166) obtained from four public and one private datasets. The CBF maps were measured using pseudo-continuous arterial spin labelling (pCASL) MRI and registered to age-specific structural templates derived from corresponding T1-weighted scans. This approach enables a more precise characterization of CBF changes associated with anatomical variations across different age groups. To ensure data reliability, rigorous quality control procedures and extensive validation at both temporal and spatial scales were conducted. These openly accessible atlases serve as a valuable public neuroimaging resource, facilitating the identification of CBF patterns across various stages of development and aging. Additionally, they provide age- and sex-specific health priors, aiding in the detection of abnormal CBF associated with brain disorders throughout the lifespan.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.