Evidence map›Paper›PMID 40634631›Full record

ArticleJournal of cancer research and clinical oncology2025

Evaluation of patient management of (radio-)chemotherapy-caused mucositis with the goal of enhancing patient treatment.

Helena Wolff, Bijan Zomorodbakhsch, Martin Schnizer, Christian Keinki, Jutta Hübner

Abstract read
In one paragraph

Article in Journal of cancer research and clinical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Helena WolffMedical Clinic II, Haematology and Internal Oncology, Jena University Hospital, Friedrich-Schiller-University, Jena, Germany. hlobo246@gmx.de.
Bijan ZomorodbakhschHaematology and Internal Oncology, MVZ Onkologische Kooperation Harz GbR, Kösliner Straße 14, Goslar, 38642, Germany.
Martin SchnizerMedical Clinic II, Haematology and Internal Oncology, Jena University Hospital, Friedrich-Schiller-University, Jena, Germany.
Christian KeinkiMedical Clinic II, Haematology and Internal Oncology, Jena University Hospital, Friedrich-Schiller-University, Jena, Germany.
Jutta HübnerMedical Clinic II, Haematology and Internal Oncology, Jena University Hospital, Friedrich-Schiller-University, Jena, Germany. Jutta.Huebner@med.uni-jena.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeOM is a very relevant and sometimes therapy-limiting side effect of CT/RCT. There are prophylactic and therapeutic measures available that should be recommended to all patients. This study investigated how patients were informed about oral mucositis (OM) as possible side effect of CT/RCT, how well they knew about available prophylactic and therapeutic measures from the clinical guidelines and to what extent they applied these.

methodsA standardized questionnaire on information and usage of prophylactic and therapeutic measures and patient-relevant outcomes based on the German S3 Guideline was distributed among patients in German cancer departments.

resultsOnly 61.6% of 114 patients were informed about OM as possible side effect by their physician and 53.2% had complaints caused by OM. An insufficient number of patients were recommended to apply prophylactic and therapeutic measures. 63.5% of the patients felt well-informed about treatment options. The most frequently recommended measure was mouth rinse (50%). Only 17.6% of patients were advised to visit a dentist.

conclusionsThe measures proposed in the German S3 guideline were insufficiently recommended. To improve patient education and the quality of care, more intensive use should be made of information flyers, training of nursing staff and greater interdisciplinary cooperation. If treatment-associated OM is to be expected, dental consultations should be firmly integrated into treatment planning.

Indexed as

Antineoplastic AgentsChemoradiotherapyNeoplasmsStomatitisAdultAgedAged, 80 and overFemaleGermanyHumansMaleMiddle AgedPatient Education as TopicPractice Guidelines as TopicSurveys and QuestionnairesAntineoplastic AgentsChemotherapyCommunicationOral mucositisPatient careRadiochemotherapy

Identifiers

PMID40634631
PMCPMC12241179

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.