Evidence map›Paper›PMID 40634685›Full record

ReviewCurrent osteoporosis reports2025

Disparities in the Diagnosis and Treatment of Osteoporosis in Persons with Cognitive Impairment and Dementia.

Pritee Shrestha, Brinda Basida, Rachel E Elam, Joanna El Hajj, Brian Le, Howard A Fink, Monique Bethel, Shafer G Tharrington, Laura D Carbone

Abstract readReview
In one paragraph

Review in Current osteoporosis reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Mental disorders and osteoporosis treatment in patients with hip fracture-a Danish population-based cohort study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
    Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Pritee ShresthaDepartment of Medicine, Division of Rheumatology, Medical College of Georgia at Augusta University, Augusta, GA, 30912, USA. PShrestha@augusta.edu.
Brinda BasidaDepartment of Medicine, Division of Rheumatology, Medical College of Georgia at Augusta University, Augusta, GA, 30912, USA.
Rachel E ElamDepartment of Medicine, Division of Rheumatology, Medical College of Georgia at Augusta University, Augusta, GA, 30912, USA.
Joanna El HajjDepartment of Medicine, Division of Rheumatology, Medical College of Georgia at Augusta University, Augusta, GA, 30912, USA.
Brian LeAugusta VA Health System, Augusta, GA, USA.
Howard A FinkGeriatric Research Education & Clinical Center, Center for Care Delivery & Outcomes Research, Minneapolis VA Health Care System, Minneapolis VA Health Care System, University of Minnesota, Minneapolis, USA.
Monique BethelDepartment of Medicine, Division of Cardiology, Medical College of Georgia at Augusta University, Augusta, USA.
Shafer G TharringtonAugusta University, Augusta, GA, USA.
Laura D CarboneDivision of Rheumatology, Department of Medicine, Distinguished University Chair in Rheumatology, Medical College of Georgia at Augusta University, Augusta, GA, USA.

Funding

Calculator for Length of Use of Bisphosphonates (CLUB) - Diversity SupplementR01AG079118 · NIA · AUGUSTA UNIVERSITY · PI LAURA D CARBONE · 2022 to 2026
$6.0M
NIA NIH HHS R01 AG079118U.S. National Institute on Aging R01AG079118
6 · The paper itself

Abstract

purpose of reviewThe purpose of this review is to summarize recently published scientific evidence (from January 1, 2020-January 1, 2025), on disparities in the diagnosis and treatment of osteoporosis and the treatment of fragility fractures in persons with cognitive impairment and dementia. RECENT

findingsWorldwide, the population is aging, and coincident with this, the number of individuals with osteoporosis and dementia is rapidly increasing. Several reports have suggested a link between these two chronic conditions. Persons with dementia who sustain an osteoporotic fracture have excess morbidity and mortality compared to similarly aged populations without cognitive impairment. However, the extent to which these differences are a function of disparities in the diagnosis and treatment of osteoporosis and treatment and rehabilitation for osteoporotic fractures is not clear. In this summary, we review the evidence that health and health care disparities exist for older adults with cognitive impairment or dementia with respect to osteoporosis diagnosis and treatment and management of fragility fractures. We highlight unique considerations for persons with cognitive impairment or dementia relative to diagnosis of osteoporosis, choice and frequency of use of osteoporosis pharmacotherapies, and consideration for rehabilitation services post hip fracture. More research is necessary to determine how best to reduce health care disparities with respect to diagnosis and treatment of osteoporosis and fragility fractures in older adults with cognitive impairment or dementia. Considerations should include early identification of persons at risk for fracture, use of osteoporosis drug therapies that require less frequent dosing and are administered by clinicians to enhance adherence, and access to patient and family-centered rehabilitation post hip fracture.

Indexed as

Cognitive DysfunctionDementiaHealthcare DisparitiesOsteoporosisOsteoporotic FracturesBone Density Conservation AgentsHumansBone Density Conservation AgentsDementiaDisparitiesFractureOsteoporosis

Identifiers

PMID40634685
PMCPMC12360041

What Socratic holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.