Evidence map›Paper›PMID 40635286›Full record

ArticleFEBS open bio2026

Microfluidic electro-viscoelastic manipulation of extracellular vesicles.

Seyedamirhosein Abdorahimzadeh, Éva Bozó, Zikrullah Bölükkaya, Artem Zhyvolozhnyi, Anatoliy Samoylenko, Henrikki Liimatainen, Seppo J Vainio, Caglar Elbuken

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in FEBS open bio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Seyedamirhosein AbdorahimzadehDisease Networks Research Unit, Faculty of Biochemistry and Molecular Medicine, University of Oulu, Finland.
Éva BozóDisease Networks Research Unit, Faculty of Biochemistry and Molecular Medicine, University of Oulu, Finland.
Zikrullah BölükkayaDisease Networks Research Unit, Faculty of Biochemistry and Molecular Medicine, University of Oulu, Finland.
Artem ZhyvolozhnyiDisease Networks Research Unit, Faculty of Biochemistry and Molecular Medicine, University of Oulu, Finland.
Anatoliy SamoylenkoDisease Networks Research Unit, Faculty of Biochemistry and Molecular Medicine, University of Oulu, Finland.ORCID https://orcid.org/0000-0002-0240-897X
Henrikki LiimatainenKvantum Institute, University of Oulu, Finland.ORCID https://orcid.org/0000-0002-7911-2632
Seppo J VainioDisease Networks Research Unit, Faculty of Biochemistry and Molecular Medicine, University of Oulu, Finland.
Caglar ElbukenDisease Networks Research Unit, Faculty of Biochemistry and Molecular Medicine, University of Oulu, Finland.ORCID https://orcid.org/0000-0001-8359-6871

Funding

Research Council of Finland GeneCellNano Flagshipthe Kvantum Institute project BioEVEngineWellcome Trust 326291
6 · The paper itself

Abstract

Microfluidic technology has created new opportunities for developing innovative tools for biological applications. Given the significance of extracellular vesicles (EVs), extensive research has focused on developing microfluidic techniques for EV isolation. This research protocol presents electro-viscoelastic microfluidics as a novel approach for manipulating EVs. The system leverages the viscoelasticity of the suspending medium along with an externally applied electric field to alter EV motion within a microchannel. These findings suggest that our electro-viscoelastic microfluidic system has the potential for further development to be used for EV isolation.

Indexed as

Extracellular VesiclesMicrofluidic Analytical TechniquesMicrofluidicsElasticityHumansViscosityelectrokineticsextracellular vesiclesmicrofabricationmicrofluidicsviscoelasticity

Identifiers

PMID40635286
PMCPMC12871555

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.