ArticleJournal of clinical neurology (Seoul, Korea)2025
Geometry and Wall Shear Stress of the Contralesional Middle Cerebral Artery Are Associated With the Burden of Cerebral Small Vessel Disease in Acute Ischemic Stroke.
Article in Journal of clinical neurology (Seoul, Korea), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
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Authors and funding
8 authors.
Funding
Abstract
background and purposeCerebral small vessel disease (cSVD) is associated with the vascular geometry of the intracranial arteries. This study aimed to determine the associations of the burden of pre-existing cSVD with the geometry and hemodynamic parameters of the middle cerebral artery (MCA) in patients with acute ischemic stroke.
methodsThis study enrolled consecutive patients with acute ischemic stroke in the MCA territory who underwent high-resolution vessel wall magnetic resonance imaging and four-dimensional flow magnetic resonance imaging in accordance with the protocol of Kyung Hee University Hospital. Patients were categorized into two groups based on the burden of pre-existing cSVD in the hemisphere contralateral to the stroke lesion: those with a modified burden score of 0-4 (low cSVD burden) and those with a modified burden score of 5-7 (high cSVD burden). The vascular geometry (straight, U-shaped, or inverted-U- and S-shaped) and wall shear stress (WSS) measured at five different points in the contralesional MCA were compared between the two burden groups.
resultsThis study included 145 patients with cSVD: 109 with a low burden and 36 with a high burden. A low cSVD burden was correlated with a U- or inverted-U-shaped MCA (
conclusionsA tortuous MCA along with an increased WSS magnitude and variability were independently associated with a high cSVD burden.
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