Evidence map›Paper›PMID 40635721›Full record

ArticleFrontiers in human neuroscience2025

The impact of interactive motor-cognitive dual tasking on brain activation, functional connectivity, and behavioral performance in healthy adults: an fNIRS study.

Xiaohan Li, Lifeng Tang, Yuting Zhang, Lin Ye, Lifeng Zhou, Min Tang

Abstract read
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Article in Frontiers in human neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiaohan LiDepartment of Neurological Rehabilitation, Ningbo Rehabilitation Hospital, Ningbo, China.
Lifeng TangFaculty of Rehabilitation, Gannan Medical University, Ganzhou, China.
Yuting ZhangFaculty of Marine, Ningbo University, Ningbo, China.
Lin YeDepartment of Neurological Rehabilitation, Ningbo Rehabilitation Hospital, Ningbo, China.
Lifeng ZhouFaculty of Health Service and Health, Ningbo College of Health Sciences, Ningbo, China.
Min TangDepartment of Neurological Rehabilitation, Ningbo Rehabilitation Hospital, Ningbo, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study aimed to explore how varying levels of interactive motor-cognitive dual task difficulty affect brain activation, functional connectivity (FC), and behavioral performance in healthy adults using functional near-infrared spectroscopy (fNIRS). Methods: We recruited 28 healthy participants to perform interactive motor-cognitive dual task at three difficulty levels: easy task (ET), medium task (MT), and difficult task (DT). The tasks involved walking while simultaneously engaging in cognitive challenges. A continuous-wave fNIRS system was used to collect fNIRS data during the task, focusing on 10 regions of interest (ROIs): left/right prefrontal cortex (LPFC/RPFC), left/right dorsolateral prefrontal cortex (DLPFC/DRPFC), left/right premotor cortex (LPMC/RPMC), left/right sensorimotor cortex (LSC/RSC), and left/right motor cortex (LMC/RMC). Simultaneously, the subjects' gait data during walking were collected using an Inertial Measurement Unit (IMU) sensor, and their cognitive performance was recorded by the researchers. Results: Statistical analysis revealed statistically significant differences in the mean HbO levels among the three groups for the DRPFC, LPMC/RPMC, RSC, and LMC/RMC regions. Additionally, significant differences were found in the activation of channels 3, 18, 24, 25, 28, and 29 across the three groups. The group-averaged FC in the DT (0.61 ± 0.21) was significantly higher than that in the ET (0.46 ± 0.21, Conclusion: We found that increased task difficulty heightened activation in the premotor and motor cortices, with a tendency toward right hemisphere dominance. Higher task difficulty also strengthened FC, particularly in motor-related regions, indicating greater neural coordination. Behaviorally, participants exhibited slower gait parameters and reduced cognitive performance as task complexity increased, highlighting the impact of dual-task interference.

Indexed as

brain activationfNIRSfunctional connectivityinteractive dual tasklateralization

Identifiers

PMID40635721
PMCPMC12237959

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.