Evidence map›Paper›PMID 40635742›Full record

ArticleFrontiers in pharmacology2025

KU124 (9,10,10-trioxo-N-(2-phenylphenyl)thioxanthene-3-carboxamide) as a novel inhibitor of TASK-1.

Ana Dumani, Annette Jacob, Diego Chavez, Abena Amankwaa, Ramish Zahed, Martha Julemis, Hinaben Patel, Joana Lopez, Steven Almazan, Patrick Martins and 27 more

Abstract read
In one paragraph

Article in Frontiers in pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

37 authors.

Ana Dumani *Kean University, Union, NJ, United States.
Annette Jacob *Kean University, Union, NJ, United States.
Diego Chavez *Kean University, Union, NJ, United States.
Abena Amankwaa *Kean University, Union, NJ, United States.
Ramish Zahed *Kean University, Union, NJ, United States.
Martha Julemis *Kean University, Union, NJ, United States.
Hinaben Patel *Kean University, Union, NJ, United States.
Joana Lopez *Kean University, Union, NJ, United States.
Steven Almazan *Kean University, Union, NJ, United States.
Patrick Martins *Kean University, Union, NJ, United States.
Anthony Contreras *Kean University, Union, NJ, United States.
Sofiia KorotkaKean University, Union, NJ, United States.
Gianna KiszkaKean University, Union, NJ, United States.
Alexander AleynikKean University, Union, NJ, United States.
Justin PatinoKean University, Union, NJ, United States.
David GrahamKean University, Union, NJ, United States.
Megan BlaisdellKean University, Union, NJ, United States.
Youssef ElhowaryKean University, Union, NJ, United States.
Shuayb YousufKean University, Union, NJ, United States.
Chelsea PelleyKean University, Union, NJ, United States.
Jenna MarcianoKean University, Union, NJ, United States.
Jessica BestKean University, Union, NJ, United States.
Rhustie ValdiznoKean University, Union, NJ, United States.
Nikki MastrodomenicoKean University, Union, NJ, United States.
Jonelle BrownKean University, Union, NJ, United States.
Sarah SchwartzTouro University, New York, NY, United States.
Irene AninKean University, Union, NJ, United States.
Yara FarragKean University, Union, NJ, United States.
Rinchu GeorgeKean University, Union, NJ, United States.
Gianna MedeirosKean University, Union, NJ, United States.
Sophia LangKean University, Union, NJ, United States.
Marilyn DennisKean University, Union, NJ, United States.
Oluwatoni AwoleyeKean University, Union, NJ, United States.
Lamont LeeKean University, Union, NJ, United States.
Ericka SalgadoKean University, Union, NJ, United States.
Diana Figueroa CheaKean University, Union, NJ, United States.
Thomas Walter ComolloKean University, Union, NJ, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

TASK-1 is a two-pore K

Indexed as

inhibitorion channelKU124molecular dynamicsthallium fluxTWIK-related acid-sensitive potassium channel 1two-pore potassium channelvirtual screening

Identifiers

PMID40635742
PMCPMC12237960

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.