ArticleJournal of Indian Society of Periodontology
Comparative evaluation of tumor necrosis factor-α levels in gingival crevicular fluid, HbA1c levels, and homeostatic model assessment for insulin resistance in nondiabetic subjects with and without periodontitis.
Article in Journal of Indian Society of Periodontology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Diabetes mellitus is a well-recognized risk factor for periodontitis and there is ample evidence that untreated periodontitis can worsen glycemic control in the diabetic population. However, the effect of untreated periodontitis on glycemic status of nondiabetic population is less explored. The aim of the study is to estimate and correlate glycemic control and inflammatory status with periodontal parameters of nondiabetic subjects with and without generalized periodontitis. Materials and Methods: Nondiabetic subjects between 18 and 60 years were divided into two groups: Group 1: periodontally healthy controls ( Results: There was a statistically significant difference ( Conclusion: There is a significant difference in the HbA1c, HOMA IR, and TNF α between nondiabetic subjects with and without periodontitis indicating that untreated periodontal disease worsens the glycemic control and increases the risk of developing diabetes mellitus in nondiabetic individuals.
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