Trial reportMedical science monitor : international medical journal of experimental and clinical research2025
Quantitative Multi-Parameter MRI Evaluation of Hashimoto's Thyroiditis Changes After Dietary Interventions.
Trial report in Medical science monitor : international medical journal of experimental and clinical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
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Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND Hashimoto's thyroiditis is a common autoimmune disease. There are currently few studies utilizing multi-parametric magnetic resonance imaging (MRI) to investigate diffuse thyroid lesions such as Hashimoto's thyroiditis. This study aims to explore the value of multi-parametric MRI in assessing the progression of Hashimoto's thyroiditis. MATERIAL AND METHODS The study ultimately included 40 patients with Hashimoto's thyroiditis, who were randomly and evenly assigned to an intervention group and a control group. The intervention group received dietary management, while the control group received no intervention. Laboratory and imaging tests were conducted at baseline and 6 months later. RESULTS After dietary management, patients with Hashimoto's thyroiditis showed a significant reduction in thyroid T2-weighted imaging relative signal intensity (T2WI RSI) (mean: 1.69±0.35 vs 1.42±0.24, P<0.05) and water fraction (mean: 94.57±1.76 vs 93.36±1.62, P<0.001). Additionally, thyroid peroxidase antibody (TPOAb) and thyroglobulin antibody (TGAb) levels decreased significantly (TPOAb: 376.58±319.52 vs 273.55±287.63, P<0.05; TGAb: 219.06±572.54 vs 198.80±567.59, P<0.05). In contrast, no significant changes in thyroid water fraction, TPOAb, or TGAb levels were observed in the control group (P>0.05). CONCLUSIONS In conclusion, multi-parametric MRI offers a valuable quantitative tool for assessing Hashimoto's thyroiditis, providing an intuitive and sensitive method to improve disease understanding and management.
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Registered trials
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