Evidence mapPaperPMID 40640291Full record

ArticleScientific reports2025

Impact of major congenital anomalies on preterm birth and low birth weight.

Hiba Adam, Nadirah Ghenimi, Anne F Minsart, Hassib Narchi, Shamsa Al Awar, Omniyat M Al Hajeri, Iffat Elbarazi, Rami H Al-Rifai, Luai A Ahmed

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Association of preterm birth and congenital anomalies: findings of a Brazilian multicenter study.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2026
    Article
  5. Temporal trends and factors associated with live preterm births in Espírito Santo, 2012-2021.Revista brasileira de epidemiologia = Brazilian journal of epidemiology · 2026
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hiba AdamInstitute of Public Health, College of Medicine and Health Sciences, United Arab Emirates University, P.O. Box 15551, Al Ain, UAE. 202190143@uaeu.ac.ae.
Nadirah GhenimiDepartment of Family Medicine, College of Medicine and Health Sciences, United Arab Emirates University, P.O. Box 15551, Al Ain, UAE.
Anne F MinsartDivision of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Mediclinic Middle East, Dubai, UAE.
Hassib NarchiDepartment of Pediatrics, College of Medicine and Health Sciences, United Arab Emirates University, P.O. Box 15551, Al Ain, UAE.
Shamsa Al AwarDepartment of Obstetrics and Gynecology, College of Medicine and Health Sciences, United Arab Emirates University, P.O. Box 15551, Al Ain, UAE.
Omniyat M Al HajeriCommunity Health Sector, Abu Dhabi Public Health Center, P.O. Box 5674, Abu Dhabi, UAE.
Iffat ElbaraziInstitute of Public Health, College of Medicine and Health Sciences, United Arab Emirates University, P.O. Box 15551, Al Ain, UAE.
Rami H Al-RifaiInstitute of Public Health, College of Medicine and Health Sciences, United Arab Emirates University, P.O. Box 15551, Al Ain, UAE.
Luai A AhmedInstitute of Public Health, College of Medicine and Health Sciences, United Arab Emirates University, P.O. Box 15551, Al Ain, UAE.

Funding

Zayed Centre for Health Sciences, United Arab Emirates University Grant # 31R239
6 · The paper itself

Abstract

Major congenital anomalies (MCAs) are significant contributors to perinatal morbidity and mortality, especially in preterm and low birth weight neonates. The association between MCAs, preterm birth, and low birth weight remains poorly defined, necessitating further research to refine management strategies. This study aimed to investigate the impact of MCAs on preterm and low birth weight births in a sample of the Emirati population. The analysis was based on a cohort of singleton live births from the Mutaba'ah study (2017-2023). Regression models assessed the association between MCAs and both preterm birth and low birth weight, adjusting for maternal and neonatal characteristics. Neonates with any MCAs had two-times higher odds of preterm birth (adjusted odds ratio (AOR): 2.0, 95% confidence interval (CI) 1.3-2.9) and low birth weight (AOR: 2.2, 95% CI 1.4-3.3), compared with MCAs-free neonates. Moreover, neonates with multiple MCAs had significantly increased odds of being born preterm (AOR: 5.3, 95% CI 2.6-10.7) or with low birth weight (AOR: 3.5, 95% CI 1.5-8.6). This study provides evidence of a strong association between MCAs and increased risks of preterm birth and low birth weight, highlighting the need for a proactive, multidisciplinary approach to improve health outcomes for this vulnerable population.

Indexed as

Congenital AbnormalitiesInfant, Low Birth WeightPremature BirthAdultFemaleHumansInfant, NewbornMaleOdds RatioPregnancyRisk FactorsUnited Arab EmiratesCohortLow birth weightMajor congenital anomaliesNeonatesPerinatalPreterm birthUnited Arab Emirates

Identifiers

PMID40640291
PMCPMC12246164

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.