ArticleScientific reports2025
Effects of tea polysaccharides on gut microbiota and physiological health indicators in mice.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Medicinal Value ofInternational journal of molecular sciences · 2026Review
- Multi-Component Botanical Crude Extracts Improve Egg and Meat Quality in Late-Laying Hens Through Gut Microbiota Modulation.Foods (Basel, Switzerland) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tea polysaccharide (TPS) is a naturally occurring polysaccharide that has garnered increasing attention due to its remarkable biological activity and significant potential for application. This study focused on examining the alterations in gut microbiota composition and the physiological health of mice subjected to TPS exposure. In this study, a control group (CTRL), a high-dose TPS group (TPH), and a low-dose TPS group (TPL) were established to investigate the effects of TPS on the physiological condition of the intestinal microbiota, liver, intestines, and blood in mice. The findings indicated that TPS significantly increased the relative abundance of beneficial probiotics, including Bacteroidota and Muribaculum, while concurrently diminishing the relative abundance of detrimental intestinal bacteria such as Prevotella_copri and Desulfovibrionia. Additionally, with respect to health indicators, TPS was found to effectively lower the glutamate-glutamate ratio (AST/ALT) and creatine kinase (CK). Serum amylase (AMY) and glucose (Glu) levels were elevated in TPH mice, suggesting improved glucose metabolism. Beta-diversity analysis showed distinct clustering of microbial communities in TPL group, though alpha diversity remained unchanged across groups. Histopathological analysis confirmed no adverse effects on liver or intestinal integrity. Correlation heatmaps highlighted significant associations between gut microbiota (e.g., Bacteroides_H) and metabolic markers (e.g., CO
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.