Evidence map›Paper›PMID 40640586›Full record

ArticleCell biochemistry and biophysics2025

Increased Cell Growth Response to Lysophosphatidic Acid (LPA) of Lung Cancer Cells via LPA Receptor Signaling Induced by Cooperative Action of Lymphatic Endothelial Cells and Fibroblasts.

Yuka Kusumoto, Shion Nagano, Moemi Tamura, Nanami Shimomura, Narumi Yashiro, Mao Yamamoto, Miwa Takai, Toshifumi Tsujiuchi

Abstract read
PubMed Publisher
In one paragraph

Article in Cell biochemistry and biophysics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yuka KusumotoDivision of Molecular Oncology, Department of Life Science, Faculty of Science and Engineering, Kindai University, Osaka, Japan.
Shion NaganoDivision of Molecular Oncology, Department of Life Science, Faculty of Science and Engineering, Kindai University, Osaka, Japan.
Moemi TamuraDivision of Molecular Oncology, Department of Life Science, Faculty of Science and Engineering, Kindai University, Osaka, Japan.
Nanami ShimomuraDivision of Molecular Oncology, Department of Life Science, Faculty of Science and Engineering, Kindai University, Osaka, Japan.
Narumi YashiroDivision of Molecular Oncology, Department of Life Science, Faculty of Science and Engineering, Kindai University, Osaka, Japan.
Mao YamamotoDivision of Molecular Oncology, Department of Life Science, Faculty of Science and Engineering, Kindai University, Osaka, Japan.
Miwa TakaiDivision of Molecular Oncology, Department of Life Science, Faculty of Science and Engineering, Kindai University, Osaka, Japan.
Toshifumi TsujiuchiDivision of Molecular Oncology, Department of Life Science, Faculty of Science and Engineering, Kindai University, Osaka, Japan. ttujiuch@life.kindai.ac.jp.

Funding

Japan Society for the Promotion of Science JP18K07249
6 · The paper itself

Abstract

Lysophosphatidic acid (LPA) receptors (LPA

Indexed as

Endothelial CellsFibroblastsLung NeoplasmsLysophospholipidsReceptors, Lysophosphatidic AcidSignal TransductionA549 CellsAnimalsCell ProliferationCoculture TechniquesHumansIsoxazolesLysophospholipase DMicePhosphoric Diester HydrolasesPropionates3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl amino)-3-methyl-5-isoxazolyl) benzylsulfanyl) propanoic acidIsoxazoleslysophosphatidic acidLysophospholipase DLysophospholipidsPhosphoric Diester HydrolasesPropionatesReceptors, Lysophosphatidic AcidCell growthFibroblastsLPA receptorsLung cancer cellsLymphatic endothelial cells

Identifiers

PMID40640586

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.