Evidence map›Paper›PMID 40640737›Full record

ArticleBMC pregnancy and childbirth2025

Associations between maternal visceral fat in mid-pregnancy and subsequent gestational diabetes mellitus in a Chinese population: a cohort study.

Xiao-Wei Dai, Xue-Mei Fan, Ye Yu, Miao Yu, Ting-Ting Li, Kang Yu

Abstract read
In one paragraph

Article in BMC pregnancy and childbirth, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Xiao-Wei DaiShenzhen Nanshan Maternity and Child Healthcare Hospital, Shenzhen, People's Republic of China.
Xue-Mei FanShenzhen Nanshan Maternity and Child Healthcare Hospital, Shenzhen, People's Republic of China.
Ye YuShenzhen Nanshan Maternity and Child Healthcare Hospital, Shenzhen, People's Republic of China.
Miao YuShenzhen Nanshan Maternity and Child Healthcare Hospital, Shenzhen, People's Republic of China.
Ting-Ting LiShenzhen Nanshan Maternity and Child Healthcare Hospital, Shenzhen, People's Republic of China.
Kang YuDepartment of Clinical Nutrition, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences(CAMS) and Peking Union Medical College(PUMC), Beijing, People's Republic of China. yuk1997@sina.com.

Funding

Sanming Project of Medicine in Shenzhen Nanshan No.202408Shenzhen Science and Technology Program JCYJ20210324140808022
6 · The paper itself

Abstract

backgroundMaternal obesity is an established risk factor for gestational diabetes mellitus (GDM). This study aimed to investigate the association between ultrasound-measured visceral adipose tissue and GDM risk in lean Chinese pregnant women.

methodsA prospective cohort study of pregnant women aged 18-45 years with a singleton pregnancy was conducted in Shenzhen Nanshan Maternity and Child Healthcare Hospital, China, between May 2022 and October 2022. Ultrasound measurements of abdominal subcutaneous (SAT) and visceral adipose tissue (VAT) depth were performed at 21-23 weeks' gestation. GDM diagnosis was performed using 75 g oral glucose tolerance test (OGTT) at 24-28 weeks' gestation. After adjustment for maternal age, parity, family history of diabetes, educational level, and pre-pregnancy body mass index (BMI), log-binomial model was used to analyze the associations of ultrasound measurements of VAT and SAT with GDM. A receiver-operating characteristic (ROC) curve analysis was conducted to assess the predictive value of VAT and SAT for new-onset GDM.

resultsAmong 550 women included, 141 subjects (25.6%) developed GDM. The mean maternal age (32.9 ± 4.8 vs. 30.7 ± 4.2 year, P < 0.001) and the mean pre-pregnancy BMI (22.05 ± 2.95 vs. 20.76 ± 2.46 kg/m

conclusionsUltrasound-measured abdominal VAT during mid-pregnancy is a potential clinical tool for improving sensitivity of early risk stratification for GDM in non-obese pregnant women.

Indexed as

Diabetes, GestationalIntra-Abdominal FatAdolescentAdultBody Mass IndexChinaCohort StudiesEast Asian PeopleFemaleGlucose Tolerance TestHumansMiddle AgedPregnancyPregnancy Trimester, SecondProspective StudiesRisk FactorsChinese pregnant womenGestational diabetesMaternal visceral obesityUltrasound

Identifiers

PMID40640737
PMCPMC12243135

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.