Evidence map›Paper›PMID 40641461›Full record

Observational studyFuture cardiology2025

Qualitative analysis of experiences, burdens, and needs among patients with hypertrophic cardiomyopathy in Japan.

Yuichiro Maekawa, Yuika Ikeda, Makio Torigoe, Kanako Shimoura, Shintaro Suo, Ryohei Takeda, Hiroaki Kitaoka

Registry-linked trialAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Future cardiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06181617 (Health-Related Quality of Life in Patients With Hypertrophic Cardiomyopathy in Japan), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06181617 completednot on this map

Health-Related Quality of Life in Patients With Hypertrophic Cardiomyopathy in Japan

TypeobservationalSponsorBristol-Myers SquibbRan2023 to 2025Enrolled149ConditionsHypertrophic CardiomyopathyArmsQuality of life assessment
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yuichiro MaekawaDivision of Cardiology, Internal Medicine III, Hamamatsu University School of Medicine, Hamamatsu, Japan.
Yuika IkedaHealth Economics and Outcomes Research, Bristol Myers Squibb, Tokyo, Japan.
Makio TorigoeJapan Medical, Bristol Myers Squibb, Tokyo, Japan.
Kanako ShimouraPatient Outcome Team, Medical Science and Writing Group, Mebix, Inc., Tokyo, Japan.
Shintaro SuoPatient Outcome Team, Medical Science and Writing Group, Mebix, Inc., Tokyo, Japan.
Ryohei TakedaPatient Outcome Team, Medical Science and Writing Group, Mebix, Inc., Tokyo, Japan.
Hiroaki KitaokaDepartment of Cardiology and Geriatrics, Kochi Medical School, Kochi University, Kochi, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo identify factors affecting the health-related quality of life (HR-QOL) of symptomatic patients with hypertrophic cardiomyopathy (HCM) using qualitative interviews exploring patients' experiences and perceptions. PATIENTS &

methodsThis cross-sectional observational study was conducted using qualitative web-based or telephone interviews. Adult patients with HCM in Japan who were experiencing burden because of HCM were included. In-depth interviews were conducted using a semi-structured interview guide. The data were analyzed using a thematic analysis approach.

resultsNineteen patients completed the interview. Ten HR-QOL-related themes were identified. Many patients were unaware that they had HCM symptoms, either no longer noticing them following life adjustments or attributing them to factors other than HCM. HCM affected multiple life aspects, including work, family, and social life. Patients resisted disclosing their disease to others and strongly resisted invasive treatment. Patients highly trusted their physicians but were reluctant to discuss their mental burdens and daily life challenges with them.

conclusionsThis first qualitative study of HR-QOL in patients with HCM in Japan suggests that deeper physician - patient communication is needed to understand patient burden and needs, as patients have difficulty discussing their burdens with physicians and may lack awareness of HCM symptoms. CLINICAL

trial registrationNCT06181617 (ClinicalTrials.gov).

Indexed as

Cardiomyopathy, HypertrophicCost of IllnessQuality of LifeAdultAgedCross-Sectional StudiesFemaleHumansJapanMaleMiddle AgedPhysician-Patient RelationsQualitative ResearchActivities of daily livingburdenexperiencehypertrophic cardiomyopathyJapanobservationalpatient interviewquality of life

Identifiers

PMID40641461
PMCPMC12330237

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.