Evidence map›Paper›PMID 40641621›Full record

ArticleFrontiers in aging neuroscience2025

Regional network covariance patterns of white matter integrity related to cardiorespiratory fitness in healthy aging.

Samantha G Smith, Pradyumna K Bharadwaj, David A Raichlen, Matthew D Grilli, Jessica R Andrews-Hanna, Georg A Hishaw, Matthew J Huentelman, Theodore P Trouard, Gene E Alexander

Abstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Samantha G SmithDepartment of Psychology, University of Arizona, Tucson, AZ, United States.
Pradyumna K BharadwajDepartment of Psychology, University of Arizona, Tucson, AZ, United States.
David A RaichlenHuman and Evolutionary Biology Section, Department of Biological Sciences, University of Southern California, Los Angeles, CA, United States.
Matthew D GrilliDepartment of Psychology, University of Arizona, Tucson, AZ, United States.
Jessica R Andrews-HannaDepartment of Psychology, University of Arizona, Tucson, AZ, United States.
Georg A HishawDepartment of Neurology, University of Arizona, Tucson, AZ, United States.
Matthew J HuentelmanEvelyn F. McKnight Brain Institute, University of Arizona, Tucson, AZ, United States.
Theodore P TrouardEvelyn F. McKnight Brain Institute, University of Arizona, Tucson, AZ, United States.
Gene E AlexanderDepartment of Psychology, University of Arizona, Tucson, AZ, United States.

Funding

Research Education ComponentP30AG019610 · NIA · SUN HEALTH RESEARCH INSTITUTE · PI REIMAN, ERIC MICHAEL · 2001 to 2020
$32.5M
Research Education ComponentP30AG072980 · NIA · BANNER HEALTH · PI ALIREZA ATRI · 2021 to 2026
$24.9M
Revitalizing Cognition in Older Adults at Risk for Alzheimer's Disease with Near-Infrared Photobiomodulation: Diversity SupplementR01AG064587 · NIA · UNIVERSITY OF FLORIDA · PI ALEXANDER, GENE E, BOWERS, DAWN · 2019 to 2023
$4.0M
Inactivity, sedentary behavior, and the risk for Alzheimer’s disease in middle aged to older adultsR01AG072445 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI GENE E ALEXANDER, Yann Charles Klimentidis · 2022 to 2026
$3.3M
Neuroanatomical Substrates of Aging & Cognitive DeclineR01AG025526 · NIA · UNIVERSITY OF ARIZONA · PI ALEXANDER, GENE E · 2006 to 2010
$2.2M
Physical activity predictors of cognitive and brain health in the risk for Alzheimer's diseaseR56AG067200 · NIA · UNIVERSITY OF ARIZONA · PI ALEXANDER, GENE E, RAICHLEN, DAVID · 2020 to 2020
$767k
NIA NIH HHS P30 AG019610NIA NIH HHS P30 AG072980NIA NIH HHS R01 AG025526NIA NIH HHS R01 AG064587NIA NIH HHS R01 AG072445NIA NIH HHS R56 AG067200
6 · The paper itself

Abstract

Cardiorespiratory fitness (CRF), measured by VO

Indexed as

brain agingdiffusion-weighted imagingmultivariate analysesscaled subprofile modelVO2max

Identifiers

PMID40641621
PMCPMC12241056

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.