Evidence mapPaperPMID 40641971Full record

ReviewFrontiers in medicine2025

Targeting ion channel networks in diabetic kidney disease: from molecular crosstalk to precision therapeutics and clinical innovation.

Wenfeng Wang, Bi Ke, Chen Wang, Xiaojing Xiong, Xiuyuan Feng, Hua Yan

Abstract readReview
In one paragraph

Review in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Piezo channels in tumors.Journal of cancer research and clinical oncology · 2026
    Review
  3. Review
  4. Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wenfeng Wang *Department of Cardiology, Wuhan Asia General Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, Hubei, China.
Bi Ke *Department of Cardiology, Ezhou Central Hospital, Ezhou, Hubei, China.
Chen Wang *Department of Cardiology, Wuhan Asia General Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, Hubei, China.
Xiaojing XiongDepartment of Cardiology, Wuhan Asia General Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, Hubei, China.
Xiuyuan FengDepartment of Cardiology, Ezhou Central Hospital, Ezhou, Hubei, China.
Hua YanDepartment of Cardiology, Ezhou Central Hospital, Ezhou, Hubei, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetic kidney disease (DKD), a major microvascular complication of diabetes, is closely associated with functional imbalances in ion channels regulating sodium (Na

Indexed as

diabetic kidney diseaseion channelsprecision medicinesodium-glucose cotransporter 2targeted therapy

Identifiers

PMID40641971
PMCPMC12241016

What Socratic holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.