ReviewOncology letters2025
Histone lactylation: A new frontier in laryngeal cancer research (Review).
Review in Oncology letters, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Lactylation‑mediated ferroptosis: A novel mechanism and therapeutic prospects in human diseases (Review).International journal of molecular medicine · 2026Review
- Post-translational protein lactylation modification in lung cancer: an emerging targeted therapeutic strategy.Frontiers in immunology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Laryngeal cancer is a common malignant tumor of the head and neck, and its occurrence and development are closely related to epigenetic modifications. Histone lactylation, a novel form of epigenetic modification, regulates gene expression and is involved in processes such as tumor metabolic reprogramming, shaping the tumor microenvironment, maintaining tumor stem cell characteristics and developing treatment resistance. The present review highlighted the molecular mechanisms and detection methods of histone lactylation and explores its potential role in laryngeal cancer, as it may serve as a valuable biomarker for diagnosis and prognosis. Furthermore, targeting the lactylation pathway may provide novel therapeutic strategies, with the potential to improve treatment outcomes for patients. Overall, understanding the role of histone lactylation in laryngeal cancer may potentially lead to innovative diagnostic and therapeutic approaches and improve the management of laryngeal cancer in the future.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.