Evidence map›Paper›PMID 40643374›Full record

SynthesisPathogens and global health2025

Prevalence of oral human papillomavirus infection in African countries: a systematic review and meta-analysis.

Giorgia Della Polla, Grazia Miraglia Del Giudice, Mario Postiglione, Italo Francesco Angelillo

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Pathogens and global health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Giorgia Della PollaDepartment of Experimental Medicine, University of Campania "Luigi Vanvitelli", Naples, Italy.
Grazia Miraglia Del GiudiceDepartment of Experimental Medicine, University of Campania "Luigi Vanvitelli", Naples, Italy.
Mario PostiglioneDepartment of Experimental Medicine, University of Campania "Luigi Vanvitelli", Naples, Italy.
Italo Francesco AngelilloDepartment of Experimental Medicine, University of Campania "Luigi Vanvitelli", Naples, Italy.ORCID 0000-0003-1213-6602

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This meta-analysis aimed to provide pooled overall prevalence estimates of oral human papillomavirus (HPV) infection in Africa. A literature search for cross-sectional studies was conducted until January 2025. The Newcastle-Ottawa Scale assessed the methodological quality. Random-effects model estimated the pooled prevalence of oral HPV infection. Sub-group analyses were conducted using study characteristics as covariates. Thirty-three studies involving 4.607 participants from 9 countries were included. Prevalence of oral HPV infection ranged between 0% to 95.1%, with a pooled overall estimate of 15.8%. The studies exhibited considerable heterogeneity (I2 = 99.3%). Subgroup analyses revealed the highest prevalence among participants with head and neck cancer (19.9%), from sub-Saharan area (19.2%), female (17.3%), moderate-low-quality studies (16.7%), and in HIV-positive (5.8%). High-quality studies with an accurate collection of the risk factors are needed for tailoring programs and health-care policies to prevent and control oral HPV infection and associated diseases.

Indexed as

Mouth DiseasesPapillomaviridaePapillomavirus InfectionsAfricaCross-Sectional StudiesFemaleHumansMalePrevalenceRisk FactorsAfricameta-analysismouth diseasesoral human papillomavirus infectionprevalencesystematic review

Identifiers

PMID40643374
PMCPMC12459196

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.