Evidence map›Paper›PMID 40643662›Full record

ArticleHNO2025

[Laryngopharyngeal reflux disease-update 2025 : Revision taking into consideration the European CEORL-HNS guideline].

Arne Böttcher, Lisa Schmitz, Mihnea C Trache, Ulrich Stortz, Jacob F Clausen, Christian S Betz

Abstract readEnglish Abstract
PubMed Publisher
In one paragraph

Article in HNO, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Arne BöttcherKlinik und Poliklinik für Hals‑, Nasen- und Ohrenheilkunde, Kopf- und Neurozentrum, Universitätsklinikum Hamburg-Eppendorf, Martinistraße 52, 20251, Hamburg, Deutschland. ar.boettcher@uke.de.ORCID http://orcid.org/0000-0001-8996-978X
Lisa SchmitzKlinik und Poliklinik für Hals‑, Nasen- und Ohrenheilkunde, Kopf- und Neurozentrum, Universitätsklinikum Hamburg-Eppendorf, Martinistraße 52, 20251, Hamburg, Deutschland.
Mihnea C TracheKlinik und Poliklinik für Hals‑, Nasen- und Ohrenheilkunde, Kopf- und Neurozentrum, Universitätsklinikum Hamburg-Eppendorf, Martinistraße 52, 20251, Hamburg, Deutschland.
Ulrich StortzKlinik für Innere Medizin I: Gastroenterologie, Schwarzwald-Baar Klinikum, Villingen-Schwenningen, Deutschland.
Jacob F ClausenKlinik und Poliklinik für Hals‑, Nasen- und Ohrenheilkunde, Kopf- und Neurozentrum, Universitätsklinikum Hamburg-Eppendorf, Martinistraße 52, 20251, Hamburg, Deutschland.
Christian S BetzKlinik und Poliklinik für Hals‑, Nasen- und Ohrenheilkunde, Kopf- und Neurozentrum, Universitätsklinikum Hamburg-Eppendorf, Martinistraße 52, 20251, Hamburg, Deutschland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Laryngopharyngeal reflux disease (LPRD), a common condition with a variety of symptoms, often occurs without heartburn. One of the main causes appears to be the pepsin effect. Systematic recording of symptoms and findings confirms the suspected diagnosis. A patient-individualized multimodal therapy plan can quickly provide relief. Lifestyle modifications and treatment with alginate and proton pump inhibitors are often effective. Carcinophobic patients with foreign body sensation should be informed in detail and, in case of doubt, malignancy should be ruled out. This CME training course provides an overview of the current state of knowledge and refers to the recently published European guideline of the Confederation of European Otorhinolaryngology-Head and Neck Surgery Societies (CEORL-HNS).

Indexed as

Laryngopharyngeal RefluxOtolaryngologyPractice Guidelines as TopicCombined Modality TherapyEuropeEvidence-Based MedicineHumansProton Pump InhibitorsProton Pump InhibitorsDeglutition disordersDysphoniaEsophageal motility disordersLifestyleProton pump inhibitors

Identifiers

PMID40643662

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.