Evidence map›Paper›PMID 40643741›Full record

ArticleArchives of microbiology2025

Synergistic antimicrobial effect and mechanism of enterocin Gr17 and cinnamaldehyde against Escherichia coli and Candida albicans.

Wen-Yu Ma, Kai-Sheng Shen, Zhao Wang, Qi Liu, Xin-Jie Diao, Guo-Rong Liu

Abstract read
PubMed Publisher
In one paragraph

Article in Archives of microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Effect ofPathogens (Basel, Switzerland) · 2026
    Article
  2. Article
  3. Article
  4. Antimicrobial effects of essential oil fromFrontiers in cellular and infection microbiology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wen-Yu Ma *School of Food and Health, Beijing Technology and Business University, East campus of Beijing Technology and Business University, No.11 of Fucheng Road, Haidian District, Beijing, 100048, China.
Kai-Sheng Shen *School of Food and Health, Beijing Technology and Business University, East campus of Beijing Technology and Business University, No.11 of Fucheng Road, Haidian District, Beijing, 100048, China.
Zhao WangSchool of Food and Health, Beijing Technology and Business University, East campus of Beijing Technology and Business University, No.11 of Fucheng Road, Haidian District, Beijing, 100048, China.
Qi LiuSchool of Food and Health, Beijing Technology and Business University, East campus of Beijing Technology and Business University, No.11 of Fucheng Road, Haidian District, Beijing, 100048, China.
Xin-Jie DiaoSchool of Food and Health, Beijing Technology and Business University, East campus of Beijing Technology and Business University, No.11 of Fucheng Road, Haidian District, Beijing, 100048, China.
Guo-Rong LiuSchool of Food and Health, Beijing Technology and Business University, East campus of Beijing Technology and Business University, No.11 of Fucheng Road, Haidian District, Beijing, 100048, China. liuguorong@th.btbu.edu.cn.

Funding

Basic and Applied Basic Research Foundation of Guangdong Province No. 2022A1515140021National Natural Science Foundation of China No. 31871772This project was funded by Beijing Natural Science Foundation No. 6252001
6 · The paper itself

Abstract

Bacteriocins and essential oils have potential synergistic antimicrobial effects against pathogens, but the poor understanding of their antimicrobial mechanisms, especially against Gram-negative bacteria and fungi, restricts their practical use in public health. Enterocin Gr17 (ENT) is a novel class IIa bacteriocin that exhibits synergistic effects with cinnamaldehyde essential oil (CEO) against some pathogenic Gram-negative bacteria and fungi. This study aimed to further understand the synergistic antimicrobial activity and mechanisms of ENT and CEO against pathogenic Escherichia coli and Candida albicans from the perspectives of cell wall and membrane, morphological structure, respiratory metabolism and gene expression. Results showed that the ENT-CEO combination induced sublethal damage to E. coli and C. albicans, synergistically limiting their growth in a time-dependent manner. For E. coli, ENT and CEO synergistically disrupted the cell wall structure via interfering with membrane potential and targeting cell wall components, then enhanced membrane permeability and formed non-selective pores, leading to K

Indexed as

AcroleinBacteriocinsCandida albicansEscherichia coliCell WallDrug SynergismMicrobial Sensitivity TestsOils, VolatileAcroleinBacteriocinscinnamaldehydeOils, VolatileCinnamaldehydeEnterocin Gr17Fungi pathogenGram-negative pathogenSynergistic antimicrobial mechanism

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.