Evidence mapPaperPMID 40643876Full record

GuidelineCurrent medical science2025

Expert Consensus on Clinical Application of Implantable Biventricular Assist Devices.

Nian-Guo Dong, David D'Alessandro, Jamshid Karimov, I-Wen Wang, Liang-Wan Chen, Ying-Bin Xiao, Chun-Sheng Wang, Qiang Zhao, Jia-Wei Shi, Shun-Zhou Yu and 19 more

Abstract readConsensus StatementPractice Guideline
PubMed Publisher
In one paragraph

Guideline in Current medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors.

Nian-Guo Dong *Department of Cardiovascular Surgery, Union Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China. dongnianguo@hust.edu.cn.
David D'AlessandroDivision of Cardiac Surgery, Massachusetts General Hospital, Boston, 02114, USA. DADALESSANDRO@mgh.harvard.edu.
Jamshid KarimovDepartment of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, Cleveland, 44106, USA. karimoj@ccf.org.
I-Wen WangDivision of Cardiac Surgery, Memorial Healthcare System, Hollywood, 33021, USA. IWang@mhs.net.
Liang-Wan ChenDepartment of Cardiac Surgery, Union Hospital, Fujian Medical University, Fuzhou, 350001, China.
Ying-Bin XiaoDepartment of Cardiovascular Surgery, The Second Affiliated Hospital, Army Medical University, Chongqing, 400037, China.
Chun-Sheng WangDepartment of Cardiovascular Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Qiang ZhaoDepartment of Cardiovascular Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.
Jia-Wei Shi *Department of Cardiovascular Surgery, Union Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Shun-Zhou YuShenzhen Core Medical Technology Co., Ltd., Shenzhen, 518000, China.
Cheng Zhou *Department of Cardiovascular Surgery, Union Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Pascal LeprinceDepartment of Cardio-Thoracic Surgery, Pitié-Salpêtrière Hospital, Sorbonne University, 75013, Paris, France.
Minoru OnoDepartment of Cardiothoracic Surgery, The University of Tokyo, Tokyo, 113-8655, Japan.
Jan SchmittoDepartment of Cardiac, Thoracic, Transplantation and Vascular Surgery, Hannover Medical School, 30625, Hannover, Germany.
Ming GongDepartment of Cardiovascular Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, 210029, China.
Yong-Feng ShaoDepartment of Cardiovascular Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China.
Xian-Qiang WangDepartment of Cardiac Surgery, National Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, China.
Xing HaoDepartment of Cardiovascular Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, 210029, China.
Xiao-Tong HouDepartment of Cardiovascular Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, 210029, China.
Xin LiDepartment of Cardiovascular Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Wei WangDepartment of Cardiovascular Surgery, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, 200127, China.
Ting WuDepartment of Cardiopulmonary Bypass, Clinical College of Chest, Tianjin Medical University, Tianjin, 300070, China.
Hai-Tao ZhangDepartment of Critical Care Medicine, School of Medicine, Shanghai East Hospital, Tongji University, Shanghai, 200127, China.
Cheng-Bin ZhouDepartment of Cardiovascular Surgery, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangzhou, 510080, China.
Ping LiDepartment of Cardiovascular Surgery, Union Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Yin WangDepartment of Cardiovascular Surgery, Union Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Yi-Xuan WangDepartment of Cardiovascular Surgery, Union Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Jing ZhangDepartment of Cardiovascular Surgery, Union Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Extracorporeal Life Support Professional Committee, Chinese Medical Doctor Association

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While biventricular assist devices (BiVADs) remain underutilized in Western countries for biventricular heart failure (BHF), their application is expanding in China. This consensus synthesizes international guidelines, medical evidence, and Chinese clinical expertise to establish standardized protocols for BiVAD management. Key recommendations include: (1) Preoperative right heart catheterization and echocardiography for central venous pressure (CVP): pulmonary capillary wedge pressure (PCWP) ratio and pulmonary artery pulsatility index (PAPi) assessment (Class I); (2) BiVAD indication in refractory BHF or high-risk right heart failure post-left ventricular assist device (LVAD) implantation (Class IIa); (3) Right atrial implantation as the preferred surgical approach (Class IIa); (4) Warfarin-based anticoagulation (INR 2.0-2.5) with aspirin, avoiding direct oral anticoagulants (DOACs) (Class III). The guidance addresses critical gaps in patient selection, pump speed titration, and complication management, positioning integrated BiVAD systems as a promising solution for complex BHF.

Indexed as

Cardiac Resynchronization Therapy DevicesHeart-Assist DevicesHeart FailureAnticoagulantsConsensusHumansAnticoagulantsBiventricular assist deviceDouble heart failureEnd-stage heart failureHeart failure managementMechanical circulatory support

Identifiers

What Socratic holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.