Evidence map›Paper›PMID 40644600›Full record

ArticleNano letters2025

Directed Synthesis of Gold Nanoparticle Superstructures Using Self-Assembling Peptoids Containing Metal-Bonding N-Heterocyclic Carbenes.

Lingcong Ge, Thi Kim Hoang Trinh, Changning Li, Florian Mayer, Jia Min Chin, Chun-Long Chen, Michael R Reithofer

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nano letters, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lingcong GeInstitute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Währinger Straße 42, Vienna 1090, Austria.
Thi Kim Hoang TrinhPhysical Sciences Division, Pacific Northwest National Laboratory, Richland, Washington 99352, United States.ORCID 0000-0002-9906-5896
Changning LiPhysical Sciences Division, Pacific Northwest National Laboratory, Richland, Washington 99352, United States.
Florian MayerInstitute of Materials Chemistry and Research, Faculty of Chemistry, University of Vienna, Währinger Straße 42, Vienna 1090, Austria.
Jia Min ChinDepartment of Functional Materials and Catalysis, Faculty of Chemistry, University of Vienna, Währinger Straße 42, Vienna 1090, Austria.ORCID 0000-0002-0540-1597
Chun-Long ChenPhysical Sciences Division, Pacific Northwest National Laboratory, Richland, Washington 99352, United States.ORCID 0000-0002-5584-824X
Michael R ReithoferInstitute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Währinger Straße 42, Vienna 1090, Austria.ORCID 0000-0002-6328-1896

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

N-Heterocyclic carbene (NHC) ligands, with strong metal-binding affinity, offer a robust platform for constructing organic-inorganic nanohybrids with high stability and tunable properties. However, achieving precise structural control in a simple manner remains challenging. Here, we report a one-pot synthesis of nanohybrids using self-assembling peptoids functionalized with histidine-2-ylidene, which simultaneously enable peptoid assembly and NHC-metal binding. Histidine-2-ylidene-functionalized peptoids were designed to self-assemble and provide NHC binding sites, while AuNPs served as the inorganic component due to NHCs' strong affinity for gold surfaces. The resulting peptoid-NHC@AuNPs form well-defined vesicles that are characterized by UV-vis spectroscopy, X-ray photoelectron spectroscopy, and electron microscopy. Importantly, the vesicle size and morphology can be tuned via the peptoid sequence or environmental conditions. Further experiments highlight the crucial role of the NHC sites in the formation and stabilization of these nanohybrids. This modular strategy offers a versatile route to fabricating functional NHC-based nanohybrids for potential applications in sensing.

Indexed as

gold nanoparticle superstructuresnanoparticle vesiclesN-heterocyclic carbenesorganic−inorganic nanohybridself-assembling peptoids

Identifiers

PMID40644600
PMCPMC12333405

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.