Evidence map›Paper›PMID 40645944›Full record

ArticleNature communications2025

Genomic diversity and structure of prehistoric alpine individuals from the Tyrolean Iceman's territory.

Myriam Croze, Alice Paladin, Stefania Zingale, Sofia Alemanno, Franco Nicolis, Elisabetta Mottes, Frank Maixner, Annaluisa Pedrotti, Torsten Günther, Albert Zink and 1 more

Abstract readHistorical Article
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Graph transformer for ancient ancestry inference.bioRxiv : the preprint server for biology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Myriam CrozeInstitute for Mummy Studies, Eurac Research, Viale Druso 1, 39100, Bolzano, Italy.ORCID http://orcid.org/0000-0003-2164-1395
Alice PaladinInstitute for Mummy Studies, Eurac Research, Viale Druso 1, 39100, Bolzano, Italy.ORCID http://orcid.org/0000-0001-5397-195X
Stefania ZingaleInstitute for Mummy Studies, Eurac Research, Viale Druso 1, 39100, Bolzano, Italy.ORCID http://orcid.org/0000-0002-1636-4859
Sofia AlemannoInstitute for Mummy Studies, Eurac Research, Viale Druso 1, 39100, Bolzano, Italy.
Franco NicolisProvincia autonoma di Trento, UMSt Soprintendenza per i beni e le attività culturali, Ufficio beni archeologici, Via Mantova 67, 38122, Trento, Italy.
Elisabetta MottesProvincia autonoma di Trento, UMSt Soprintendenza per i beni e le attività culturali, Ufficio beni archeologici, Via Mantova 67, 38122, Trento, Italy.ORCID http://orcid.org/0000-0002-0744-1656
Frank MaixnerInstitute for Mummy Studies, Eurac Research, Viale Druso 1, 39100, Bolzano, Italy.ORCID http://orcid.org/0000-0003-2846-8994
Annaluisa PedrottiDepartment of Humanities, University of Trento, Via T. Gar, 14, 38122, Trento, Italy.
Torsten GüntherDepartment of Organismal Biology, Evolutionary Biology Centre, Uppsala University, SE- 752 36, Uppsala, Sweden.ORCID http://orcid.org/0000-0001-9460-390X
Albert ZinkInstitute for Mummy Studies, Eurac Research, Viale Druso 1, 39100, Bolzano, Italy.ORCID http://orcid.org/0000-0002-1461-747X
Valentina CoiaInstitute for Mummy Studies, Eurac Research, Viale Druso 1, 39100, Bolzano, Italy. valentina.coia@eurac.edu.ORCID http://orcid.org/0000-0002-4585-2579

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Eastern Italian Alps played a crucial bridging role between Mediterranean and Northern alpine populations since Prehistory. However, few prehistoric individuals from that region have been genomically analysed so far. Among them, the Iceman (Copper Age, 3368-3108 BC) showed a relatively high Anatolian-Neolithic-related ancestry and low Hunter-Gatherers (HGs)-related ancestry. To investigate how the genomic structure of alpine groups varied over time and to contextualize the Iceman, we analysed 47 alpine individuals dated from the Mesolithic (6380-6107 BC) to Middle Bronze Age (1601-1295 BC). The Mesolithic genome reveals genetic admixture between Western and Eastern HGs that occurred from ~13700 - 8300 BC. Most individuals from the Neolithic onwards present a genomic structure resembling that of the Iceman, supporting genetic continuity. Few individuals carry different ancestries, such as the Steppe-related ones appearing ~2400 BC. Finally, the study suggests local and non-local admixture events between HGs and Neolithic farmers from this alpine area.

Indexed as

Genetic VariationGenome, HumanDNA, AncientGenetics, PopulationGenomicsHistory, AncientHumansItalyPolymorphism, Single NucleotideDNA, Ancient

Identifiers

PMID40645944
PMCPMC12254411

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.