Evidence map›Paper›PMID 40646493›Full record

ArticleBMC infectious diseases2025

Willingness to accept Doxycycline post-exposure prophylaxis for bacterial stis prevention among men who have sex with men in Southern China: a cross-sectional analysis.

Peng Liang, Peizhen Zhao, Shujie Huang, Cheng Wang

Abstract read
In one paragraph

Article in BMC infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Peng Liang *Dermatology Hospital, Southern Medical University, Guangzhou, 510095, China.
Peizhen Zhao *Dermatology Hospital, Southern Medical University, Guangzhou, 510095, China.
Shujie HuangDermatology Hospital, Southern Medical University, Guangzhou, 510095, China.
Cheng WangDermatology Hospital, Southern Medical University, Guangzhou, 510095, China. wangcheng090705@gmail.com.

Funding

Natural Science Foundation of Guangdong Province of China 2022A1515-011454The Science and Technology Projects in Guangzhou 2024A04J4485World Health Organization-e-TDR 2024/1446181-0
6 · The paper itself

Abstract

backgroundDoxycycline post-exposure prophylaxis (doxy-PEP) has the potential to decrease the incidence of sexually transmitted infections (STIs) among men who have sex with men (MSM). However, there is a limited literature on willingness to use doxy-PEP among Chinese MSM. This study aimed to examine the willingness to use doxy-PEP and its associated factors among MSM in China.

methodsIn 2023, we conducted a cross-sectional study in four cities in Guangdong provinces in South China. Data were collected on social-demographic characteristics, sexual behaviors, and the willingness to use doxy-PEP. Multivariable logistic regression analysis was employed to identify factors associated with the willingness to use doxy-PEP.

resultsA total of 884 individuals were included in this study. Of these, 53.5% reported a willingness to use doxy-PEP for the prevention of STIs. The main concerns for those unwilling to use doxy-PEP were related to its efficacy (82.5%) and safety (81.7%). Multivariable logistic regression indicated that participants were more likely to express willingness to use doxy-PEP if they had female sexual partners in the past 6 months (adjusted Odds Ratio (aOR): 1.58, 95% CI: 1.11-2.25), had prior or current doxy-PEP use (aOR = 2.39, 95% CI: 1.13-5.05), or had peers currently using doxy-PEP (aOR = 1.58, 95% CI: 1.09-2.30).

conclusionsThe willingness to use doxy-PEP among MSM in South China is relatively low. These findings highlight the need for effective educational and targeted intervention strategies to raise awareness and knowledge toward using doxy-PEP among MSM in China.

Indexed as

Anti-Bacterial AgentsDoxycyclineHomosexuality, MalePatient Acceptance of Health CarePost-Exposure ProphylaxisSexually Transmitted DiseasesSexually Transmitted Diseases, BacterialAdolescentAdultChinaCross-Sectional StudiesHumansMaleMiddle AgedSexual BehaviorSexual PartnersAnti-Bacterial AgentsDoxycyclineChinaDoxycyclineDoxy-PEPMen who have sex with menProphylaxisSexually transmitted infections

Identifiers

PMID40646493
PMCPMC12247278

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.