Evidence map›Paper›PMID 40647004›Full record

ArticleFoods (Basel, Switzerland)2025

Exploring the Bioavailability of Red Grape Skin Extract Polyphenols: A Caco-2 Cell Model Study.

Edurne Elejalde, Rosa María Alonso, María Carmen Villarán, Lucía Díez-Gutiérrez, María Chávarri, Iratxe López-de-Armentia

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Foods (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Edurne ElejaldeTECNALIA, Basque Research and Technology Alliance (BRTA), Parque Tecnológico de Álava, 01510 Miñano, Álava, Spain.ORCID 0000-0002-8125-4445
Rosa María AlonsoFARMARTEM Group, Analytical Chemistry Department, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), 48940 Leioa, Biscay, Spain.ORCID 0000-0001-9046-6602
María Carmen VillaránTECNALIA, Basque Research and Technology Alliance (BRTA), Parque Tecnológico de Álava, 01510 Miñano, Álava, Spain.ORCID 0000-0002-0074-4224
Lucía Díez-GutiérrezTECNALIA, Basque Research and Technology Alliance (BRTA), Parque Tecnológico de Álava, 01510 Miñano, Álava, Spain.ORCID 0000-0003-0343-5635
María ChávarriTECNALIA, Basque Research and Technology Alliance (BRTA), Parque Tecnológico de Álava, 01510 Miñano, Álava, Spain.ORCID 0000-0002-2946-3039
Iratxe López-de-ArmentiaTECNALIA, Basque Research and Technology Alliance (BRTA), Parque Tecnológico de Álava, 01510 Miñano, Álava, Spain.ORCID 0000-0002-9536-416X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Grapes are a rich source of polyphenols with a positive impact on human health. Polyphenols need to be bioavailable to exert any beneficial effect. However, there is limited knowledge on the bioavailability of polyphenols in grape extracts. The intestinal permeability of nine polyphenols of a red grape skin extract (GSE) was investigated using the Caco-2 cell model that simulates the human intestinal epithelium: three anthocyanins (delphinidin-3-

Indexed as

Caco-2 cellsgrape skinintestinal permeabilityin vitro bioavailabilitypolyphenols

Identifiers

PMID40647004
PMCPMC12248599

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.