Evidence map›Paper›PMID 40647110›Full record

ReviewFoods (Basel, Switzerland)2025

The Role of Inactivation Methods in Shaping Postbiotic Composition and Modulating Bioactivity: A Review.

Ying Zhu, Meiling Xiao, Tangying Kang, Yufeng He, Jiayan Zhang, Yansheng Zhao, Xiang Xiao

Abstract readReview
In one paragraph

Review in Foods (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
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  14. Extracellular vesicles from pasteurizedFrontiers in microbiology · 2026
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ying ZhuSchool of Food and Biological Engineering, Jiangsu University, Zhenjiang 212013, China.ORCID 0000-0002-3531-235X
Meiling XiaoSchool of Food and Biological Engineering, Jiangsu University, Zhenjiang 212013, China.
Tangying KangSchool of Food and Biological Engineering, Jiangsu University, Zhenjiang 212013, China.
Yufeng HeSchool of Food and Biological Engineering, Jiangsu University, Zhenjiang 212013, China.ORCID 0000-0002-3468-2826
Jiayan ZhangSchool of Food and Biological Engineering, Jiangsu University, Zhenjiang 212013, China.
Yansheng ZhaoSchool of Food and Biological Engineering, Jiangsu University, Zhenjiang 212013, China.ORCID 0000-0002-3143-0754
Xiang XiaoSchool of Food and Biological Engineering, Jiangsu University, Zhenjiang 212013, China.

Funding

Jiangsu Provincial Key Research and Development Program BE2022353National Natural Science Foundation of China 32472305the Priority Academic Program Development of Jiangsu Higher Education Institutions PAPDZhenjiang Innovation Capacity Construction Plan - Construction of Discipline Key Laboratories SS2024005
6 · The paper itself

Abstract

Postbiotics, as the metabolic products and cellular components of probiotics, possess the characteristics of being non-living yet retaining biological activity. Postbiotics have unique advantages such as high stability, good security, and a clear target of action. In recent years, they have attracted extensive attention due to their potential roles in immune regulation, anti-inflammation, antioxidation, antibacterial activity, and improving intestinal health. This article systematically reviews the composition of postbiotics and their diversity in fermented foods, with a focus on the impact of different inactivation methods (thermal and non-thermal inactivation) on their biological activities. Many studies have shown that the choice of inactivation method directly affects the immune regulation, anti-inflammatory, and antioxidative functions of postbiotics. Additionally, this review summarizes the application potential of postbiotics in the food industry, the field of medicine and food homology, pet food, and animal breeding, and points out the challenges existing in current research. Future studies need to focus on optimizing inactivation methods to maximize the biological efficacy of postbiotics, thereby promoting the precise application of postbiotics in various fields.

Indexed as

applicationbioactivitiesinactivationpostbioticprobiotic

Identifiers

PMID40647110
PMCPMC12248574

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.