Evidence mapPaperPMID 40647148Full record

ArticleFoods (Basel, Switzerland)2025

Occurrence of Aflatoxin M1 over Three Years in Raw Milk from Croatia: Exposure Assessment and Risk Characterization in Consumers of Different Ages and Genders.

Nina Bilandžić, Ines Varga, Bruno Čalopek, Božica Solomun Kolanović, Ivana Varenina, Maja Đokić, Marija Sedak, Luka Cvetnić, Damir Pavliček, Ana Končurat

Abstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Nina BilandžićLaboratory for Residue Control, Department of Veterinary Public Health, Croatian Veterinary Institute, Savska cesta 143, 10000 Zagreb, Croatia.
Ines VargaLaboratory for Residue Control, Department of Veterinary Public Health, Croatian Veterinary Institute, Savska cesta 143, 10000 Zagreb, Croatia.ORCID 0000-0002-1089-9086
Bruno ČalopekLaboratory for Residue Control, Department of Veterinary Public Health, Croatian Veterinary Institute, Savska cesta 143, 10000 Zagreb, Croatia.
Božica Solomun KolanovićLaboratory for Residue Control, Department of Veterinary Public Health, Croatian Veterinary Institute, Savska cesta 143, 10000 Zagreb, Croatia.
Ivana VareninaLaboratory for Residue Control, Department of Veterinary Public Health, Croatian Veterinary Institute, Savska cesta 143, 10000 Zagreb, Croatia.
Maja ĐokićLaboratory for Residue Control, Department of Veterinary Public Health, Croatian Veterinary Institute, Savska cesta 143, 10000 Zagreb, Croatia.
Marija SedakLaboratory for Residue Control, Department of Veterinary Public Health, Croatian Veterinary Institute, Savska cesta 143, 10000 Zagreb, Croatia.ORCID 0000-0001-6861-0436
Luka CvetnićLaboratory for Mastitis and Raw Milk Quality, Department for Bacteriology and Parasitology, Croatian Veterinary Institute, Savska cesta 143, 10000 Zagreb, Croatia.
Damir PavličekCroatian Veterinary Institute, Veterinary Institute Križevci, Zakmardijeva 10, 48260 Križevci, Croatia.ORCID 0000-0003-1772-6257
Ana KončuratCroatian Veterinary Institute, Veterinary Institute Križevci, Zakmardijeva 10, 48260 Križevci, Croatia.ORCID 0000-0002-7520-5751

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, the frequency of aflatoxin M1 (AFM1) occurrence in raw milk was investigated across different seasons over a three-year period from 2022 to 2024 in Croatia. Risk assessment was conducted using estimated daily intake (EDI), hazard index (HI), and margin of exposure (MOE) for various age groups and both genders. The frequency of AFM1 detection above the maximum level (ML) ranged from 1.60% to 15.1%. The average incidence of AFM1 exceeding the ML was 5.67%, with the highest incidence recorded in autumn 2024. AFM1 levels within the limit of detection (LOD) and ML were found in 13% of the samples. The average mean value of AFM1 over the three-year period was 19.2 ng/kg. The highest mean AFM1 EDI values were determined for toddlers (0.61-0.67 ng/kg bw/day) and children (0.41-0.43 ng/kg bw/day). The lowest EDI values were observed in elderly females and males (0.058-0.074 ng/kg bw/day). The EDI values for females and males were slightly different. The risk assessment, based on the HI and MOE, indicated that toddlers and children are at the highest risk of exposure to AFM1, which raises significant health concerns. Additionally, consumers of large quantities of milk face a high risk of exposure, particularly during the spring and autumn seasons. For adults and the elderly, milk consumption does not pose a serious health risk.

Indexed as

aflatoxin M1cow milkCroatiaestimated daily intakesoccurrencerisk assessment

Identifiers

PMID40647148
PMCPMC12248770

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.