Evidence mapPaperPMID 40647206Full record

ReviewNutrients2025

The Role of Lifestyle Intervention in Female Fertility: A Modifiable Factor for Preconception Health.

Marisa Donato, Antonio Capalbo, Elisena Morizio, Rosa Maria Fratini, Lucrezia Pilenzi, Francesco D'Antonio, Liborio Stuppia, Ester Vitacolonna, Valentina Gatta, Fani Konstantinidou

Abstract readReview
In one paragraph

Review in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Observational
  5. Observational
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Marisa DonatoDepartment of Neuroscience, Imaging and Clinical Sciences, School of Medicine and Health Sciences, "G. d'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.ORCID 0009-0007-1624-9627
Antonio CapalboDepartment of Neuroscience, Imaging and Clinical Sciences, School of Medicine and Health Sciences, "G. d'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.
Elisena MorizioUnit of Molecular Genetics, Center for Advanced Studies and Technology (CAST), "G. d'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.
Rosa Maria FratiniDepartment of Neuroscience, Imaging and Clinical Sciences, School of Medicine and Health Sciences, "G. d'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.
Lucrezia PilenziDepartment of Neuroscience, Imaging and Clinical Sciences, School of Medicine and Health Sciences, "G. d'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.
Francesco D'AntonioCenter for Fetal Care and High-Risk Pregnancy, Department of Obstetrics and Gynaecology, "G. d'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.
Liborio StuppiaDepartment of Neuroscience, Imaging and Clinical Sciences, School of Medicine and Health Sciences, "G. d'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.
Ester VitacolonnaDepartment of Medicine and Aging, School of Medicine and Health Sciences, "G. d'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.
Valentina GattaDepartment of Neuroscience, Imaging and Clinical Sciences, School of Medicine and Health Sciences, "G. d'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.ORCID 0000-0002-9999-5823
Fani KonstantinidouDepartment of Neuroscience, Imaging and Clinical Sciences, School of Medicine and Health Sciences, "G. d'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.ORCID 0000-0002-5248-7194

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infertility is a growing global phenomenon affecting millions of individuals and is characterized by multifactorial causes, including both lifestyle and environmental factors. These include smoking, chronic exposure to environmental pollutants, stress, excessive caffeine or alcohol intake, drug use, improper eating habits and physical inactivity. The potential to modify these behaviors has gained increasing interest due to its impact on reproductive health and its role in mitigating infertility. Preconception counseling has also emerged as a fundamental strategy, providing education and risk assessments to improve pregnancy outcomes. Among lifestyle factors, nutrition, body composition and physical activity significantly influence female fertility, emphasizing the strong connection between metabolism and reproductive function. Supplementation with anti-inflammatory nutrients, such as omega-3 polyunsaturated fatty acids (

Indexed as

FertilityInfertility, FemaleLife StylePreconception CareDietDiet, MediterraneanExerciseFemaleHumansPregnancyReproductive Healthgene expressioninfertilityIVFlifestylenutritionphysical activitypreconception healthPUFAs

Identifiers

PMID40647206
PMCPMC12251342

What Socratic holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.