Evidence mapPaperPMID 40647291Full record

ReviewNutrients2025

Steatotic Liver Disease in Older Adults: Clinical Implications and Unmet Needs.

Daniel Clayton-Chubb, William W Kemp, Ammar Majeed, Peter W Lange, Jessica A Fitzpatrick, Karl Vaz, John S Lubel, Alexander D Hodge, Joanne Ryan, John J McNeil and 3 more

Abstract readReview
In one paragraph

Review in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Daniel Clayton-ChubbDepartment of Gastroenterology, Alfred Health, Melbourne 3004, Australia.ORCID 0000-0001-7479-9669
William W KempDepartment of Gastroenterology, Alfred Health, Melbourne 3004, Australia.ORCID 0000-0002-0787-7273
Ammar MajeedDepartment of Gastroenterology, Alfred Health, Melbourne 3004, Australia.
Peter W LangeDepartment of Geriatrics and General Medicine, Werribee Mercy Hospital, Werribee 3030, Australia.ORCID 0000-0002-0162-1664
Jessica A FitzpatrickDepartment of Gastroenterology, Alfred Health, Melbourne 3004, Australia.ORCID 0000-0002-7811-8135
Karl VazDepartment of Gastroenterology, Alfred Health, Melbourne 3004, Australia.ORCID 0000-0002-6427-6140
John S LubelDepartment of Gastroenterology, Alfred Health, Melbourne 3004, Australia.
Alexander D HodgeDepartment of Gastroenterology, Eastern Health, Box Hill 3128, Australia.ORCID 0000-0001-6680-2303
Joanne RyanSchool of Public Health and Preventive Medicine, Monash University, Melbourne 3004, Australia.ORCID 0000-0002-7039-6325
John J McNeilSchool of Public Health and Preventive Medicine, Monash University, Melbourne 3004, Australia.ORCID 0000-0002-1049-5129
Alice J OwenSchool of Public Health and Preventive Medicine, Monash University, Melbourne 3004, Australia.ORCID 0000-0002-4807-6069
Robyn L WoodsSchool of Public Health and Preventive Medicine, Monash University, Melbourne 3004, Australia.ORCID 0000-0003-1249-6149
Stuart K RobertsDepartment of Gastroenterology, Alfred Health, Melbourne 3004, Australia.ORCID 0000-0002-9015-7997

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metabolic dysfunction-associated steatotic liver disease (MASLD) is the commonest cause of chronic liver disease worldwide. Its incidence has been increasing rapidly, alongside the growing epidemics of type 2 diabetes mellitus and overweight/obesity. Global population age has also been increasing in parallel, and predictions indicate there will be more than 2 billion persons aged over 65 by the year 2050. The interplay between MASLD and other health conditions of older persons has been a focus of recent research. In this narrative review, we aim to describe its prevalence; clinical and sociodemographic associations; and outcomes for older persons, all of which are of significant importance when considering public health messaging as well as screening and counselling individual older adults.

Indexed as

Fatty LiverNon-alcoholic Fatty Liver DiseaseAgedAged, 80 and overFemaleHumansMalePrevalenceRisk Factorsageingcardiovascular diseasehepatologylifestyleliverMASLDmetabolic dysfunction-associated steatotic liver diseaseNAFLDolder adults

Identifiers

PMID40647291
PMCPMC12251929

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.