Evidence mapPaperPMID 40647326Full record

ReviewNutrients2025

The Biological Value of Proteins for Pediatric Growth and Development: A Narrative Review.

Marlene Fabiola Escobedo-Monge, Joaquín Parodi-Román, María Antonieta Escobedo-Monge, José Manuel Marugán-Miguelsanz

Abstract readReview
In one paragraph

Review in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Marlene Fabiola Escobedo-MongeDepartment of Pediatrics, Faculty of Medicine, University of Valladolid, Avenida Ramón y Cajal, 7, 47003 Valladolid, Spain.ORCID 0000-0002-1295-3752
Joaquín Parodi-RománScience Faculty, University of Cadiz, Paseo de Carlos III, 28, 11003 Cádiz, Spain.
María Antonieta Escobedo-MongeDepartment of Chemistry, Science Faculty, University of Burgos, Plaza Misael Bañuelos SN, 09001 Burgos, Spain.ORCID 0000-0001-6318-7333
José Manuel Marugán-MiguelsanzDepartment of Pediatrics, Faculty of Medicine, University of Valladolid, Avenida Ramón y Cajal, 7, 47003 Valladolid, Spain.ORCID 0000-0001-7255-7578

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In personalized nutrition, dietary guidelines must be adapted to the physiological and developmental needs of individuals across the lifespan, especially during childhood and adolescence. These should account for nutritional status, health conditions, and early-life risk factors, including those that emerge during pregnancy. This narrative review synthesizes recent evidence (2020-2025) on the biological value of protein sources in supporting pediatric growth and development. While adequate protein intake is essential for physical and cognitive development in individuals under nineteen, excessive intake may accelerate growth and increase the long-term risks of overweight and obesity. Compared to animal-based proteins (ABPs), plant-based proteins (PBPs) carry a higher risk of nutrient deficiencies in vulnerable populations due to lower digestibility and incomplete amino acid profiles. Although plant-based diets are encouraged for environmental reasons-particularly to reduce the ecological impact of livestock-protein intake must remain appropriate for age, sex, health status, and context. Nutritional strategies must ensure an adequate supply of essential amino acids and proper micronutrient supplementation, regardless of whether children follow diets rich in ABPs, PBPs, or a combination of both. Attention to these factors is vital to balancing nutritional adequacy with long-term health and sustainability goals.

Indexed as

Child DevelopmentChild Nutritional Physiological PhenomenaDietary ProteinsNutritive ValueAdolescentAnimal Proteins, DietaryAnimalsChildChild, PreschoolDietary SupplementsFemaleHumansInfantMaleNutritional StatusAnimal Proteins, DietaryDietary Proteinsamino acidsanimal-based proteinsbioavailabilitydigestibilitymicronutrientsplant-based proteins

Identifiers

PMID40647326
PMCPMC12252045

What Socratic holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.