Evidence map›Paper›PMID 40648946›Full record

ReviewJournal of clinical medicine2025

Safety and Efficacy of Achieving Very Low LDL Cholesterol Concentrations with PCSK9 Inhibitors.

Akshay Machanahalli Balakrishna, Sharanya Kaushik, Sangeetha Tandalam Palanivelu, Noorhan Monther, Shiva P Ponamgi, Venkata Mahesh Alla, Shantanu M Patil

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Akshay Machanahalli BalakrishnaDivision of Cardiovascular Medicine, Department of Medicine, Creighton University School of Medicine, Omaha, NE 68124, USA.ORCID 0000-0002-1219-5074
Sharanya KaushikDepartment of Internal Medicine, Jacobi Medical Center, NYC H+H, Albert Einstein College of Medicine, New York, NY 10461, USA.ORCID 0000-0002-3310-4792
Sangeetha Tandalam PalaniveluDepartment of Internal Medicine, Creighton University School of Medicine, Omaha, NE 68124, USA.ORCID 0000-0002-3367-3979
Noorhan MontherDepartment of Internal Medicine, Creighton University School of Medicine, Omaha, NE 68124, USA.ORCID 0009-0001-8663-0884
Shiva P PonamgiDivision of Cardiovascular Medicine, Department of Medicine, Creighton University School of Medicine, Omaha, NE 68124, USA.
Venkata Mahesh AllaDivision of Cardiovascular Medicine, Department of Medicine, Creighton University School of Medicine, Omaha, NE 68124, USA.
Shantanu M PatilDivision of Cardiovascular Medicine, Department of Medicine, Creighton University School of Medicine, Omaha, NE 68124, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

adverse eventsmajor adverse cardiovascular eventsPCSK9 inhibitorsvery low LDL

Identifiers

PMID40648946
PMCPMC12249667

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.