Evidence map›Paper›PMID 40649280›Full record

ArticleMolecules (Basel, Switzerland)2025

Antitumor Activity of Isalpinin from

Phisit Pouyfung, Nonthalert Lertnitikul, Hua Bai, Achitphol Chookaew, Varisa Pongrakhananon, Piriya Chonsut, Suwichak Chaisit

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Phisit PouyfungDepartment of Occupational Health and Safety, School of Public Health, Walailak University, Nakhon Si Thammarat 80160, Thailand.
Nonthalert LertnitikulDepartment of Pharmacognosy and Pharmaceutical Botany, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok 10330, Thailand.
Hua BaiCollege of Public Health, Kunming Medical University, Kunming 650500, China.ORCID 0000-0003-2683-4575
Achitphol ChookaewDivision of Hematopoiesis, Joint Research Center for Human Retrovirus Infection and Graduate School of Medical Sciences, Kumamoto University, Honjo, Chuou-ku, Kumamoto 860-0811, Japan.ORCID 0009-0006-2942-3738
Varisa PongrakhananonDepartment of Pharmacology and Physiology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok 10330, Thailand.ORCID 0000-0002-2220-0842
Piriya ChonsutDepartment of Applied Thai Traditional Medicine, School of Medicine, Walailak University, Nakhon Si Tammarat 80160, Thailand.ORCID 0000-0002-4707-3456
Suwichak ChaisitBiomass and Oil Palm Center of Excellence, Walailak University, Nakhon Si Thammarat 80160, Thailand.ORCID 0000-0003-3233-0111

Funding

Walailak University SETWU-2024-CPE-G22
6 · The paper itself

Abstract

Lung cancer is a leading cause of cancer-related deaths globally, with current treatments having significant limitations, including drug resistance, metastasis, and tumor heterogeneity. This study investigated the anticancer potential of isalpinin, a flavonoid isolated from

Indexed as

Antineoplastic Agents, PhytogenicCarcinoma, Non-Small-Cell LungLung NeoplasmsA549 CellsApoptosisCell Line, TumorCell MovementCell ProliferationCell SurvivalHumansMolecular Docking SimulationProto-Oncogene Proteins c-aktReactive Oxygen SpeciesAntineoplastic Agents, PhytogenicProto-Oncogene Proteins c-aktReactive Oxygen Speciesanchorage-independent growthanti-migrationanti-proliferationflavonoidisalpininnon-small lung cancer cellsPaphiopedilum dianthum

Identifiers

PMID40649280
PMCPMC12251045

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.