Evidence map›Paper›PMID 40649705›Full record

ArticleInternational journal of molecular sciences2025

The Effect of Parental Faecal Microbiome Transplantation from Children with Autism Spectrum Disorder on Behavior and Gastrointestinal Manifestations in the Male Offspring of Shank3 Mice.

Veronika Borbélyová, Jakub Szabó, Petronela Sušienková, Judith Potvin, Paulína Belvončíková, Tim Groß, Alžbeta Jančovičová, Zuzana Bačová, Barbara Rašková, Ivan Szadvári and 8 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Veronika BorbélyováInstitute of Molecular Biomedicine, Faculty of Medicine, Comenius University, Sasinkova 4, 811 08 Bratislava, Slovakia.ORCID 0000-0001-7014-9626
Jakub SzabóInstitute of Molecular Biomedicine, Faculty of Medicine, Comenius University, Sasinkova 4, 811 08 Bratislava, Slovakia.ORCID 0000-0002-6085-1291
Petronela SušienkováInstitute of Molecular Biomedicine, Faculty of Medicine, Comenius University, Sasinkova 4, 811 08 Bratislava, Slovakia.
Judith PotvinInstitute of Molecular Biomedicine, Faculty of Medicine, Comenius University, Sasinkova 4, 811 08 Bratislava, Slovakia.
Paulína BelvončíkováInstitute of Molecular Biomedicine, Faculty of Medicine, Comenius University, Sasinkova 4, 811 08 Bratislava, Slovakia.ORCID 0000-0003-2375-9696
Tim GroßInstitute of Molecular Biomedicine, Faculty of Medicine, Comenius University, Sasinkova 4, 811 08 Bratislava, Slovakia.
Alžbeta JančovičováInstitute of Molecular Biomedicine, Faculty of Medicine, Comenius University, Sasinkova 4, 811 08 Bratislava, Slovakia.
Zuzana BačováInstitute of Experimental Endocrinology, Biomedical Research Center, Slovak Academy of Sciences, Dúbravská cesta 9, 845 05 Bratislava, Slovakia.
Barbara RaškováInstitute of Physiology, Faculty of Medicine, Comenius University, Sasinkova 2, 813 72 Bratislava, Slovakia.ORCID 0009-0007-1988-2487
Ivan SzadváriInstitute of Physiology, Faculty of Medicine, Comenius University, Sasinkova 2, 813 72 Bratislava, Slovakia.
Matúš AntalInstitute of Experimental Endocrinology, Biomedical Research Center, Slovak Academy of Sciences, Dúbravská cesta 9, 845 05 Bratislava, Slovakia.
Zdenko PirníkInstitute of Experimental Endocrinology, Biomedical Research Center, Slovak Academy of Sciences, Dúbravská cesta 9, 845 05 Bratislava, Slovakia.
Miloslav KarhánekInstitute of Experimental Endocrinology, Biomedical Research Center, Slovak Academy of Sciences, Dúbravská cesta 9, 845 05 Bratislava, Slovakia.
Katarína ŠoltysComenius University Science Park, Comenius University, 841 04 Bratislava, Slovakia.ORCID 0000-0003-3862-3329
Roman GardlíkInstitute of Molecular Biomedicine, Faculty of Medicine, Comenius University, Sasinkova 4, 811 08 Bratislava, Slovakia.ORCID 0000-0001-8211-907X
Peter CelecInstitute of Molecular Biomedicine, Faculty of Medicine, Comenius University, Sasinkova 4, 811 08 Bratislava, Slovakia.ORCID 0000-0001-5883-3580
Daniela OstatníkováInstitute of Physiology, Faculty of Medicine, Comenius University, Sasinkova 2, 813 72 Bratislava, Slovakia.ORCID 0000-0002-4960-5057
Aleksandra TomovaInstitute of Physiology, Faculty of Medicine, Comenius University, Sasinkova 2, 813 72 Bratislava, Slovakia.

Funding

Ministry of Education, Science, Research, and Sport of the Slovak Republic VEGA 1/0062/21Slovak Research and Development Agency APVV-20-0114
6 · The paper itself

Abstract

The increasing incidence of autism spectrum disorder (ASD) increases the urgency of establishing the mechanism of its development for effective prevention and treatment. ASD's etiology includes genetic predisposition and environmental triggers, both of which can play a role in the changed microbiota. Recent research has proved the impact of maternal microbiota on the neurodevelopment of the child. To investigate the co-play of genetic and microbiota factors in ASD development, we performed fecal microbiota transplantation (FMT) from children with ASD to female

Indexed as

Autism Spectrum DisorderFecal Microbiota TransplantationNerve Tissue ProteinsAnimalsBehavior, AnimalChildDisease Models, AnimalFemaleGastrointestinal MicrobiomeHumansMaleMiceMice, KnockoutMicrofilament ProteinsPregnancyPrenatal Exposure Delayed EffectsMicrofilament ProteinsNerve Tissue ProteinsShank3 protein, mousebehaviorfecal microbiota transplantationmaternal microbiotaneurodevelopmental disorderSHANK 3 gene

Identifiers

PMID40649705
PMCPMC12249950

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.