Evidence map›Paper›PMID 40649823›Full record

ArticleInternational journal of molecular sciences2025

Metabolomic Analysis Identifies Betaine as a Key Mediator of

Liping Mei, Le Chen, Bingfei Zhang, Xianbo Jia, Xiang Gan, Wenqiang Sun

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Liping MeiKey Laboratory of Livestock and Poultry Multi-Omics, Ministry of Agriculture and Rural Affairs, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, China.
Le ChenKey Laboratory of Livestock and Poultry Multi-Omics, Ministry of Agriculture and Rural Affairs, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, China.
Bingfei ZhangKey Laboratory of Livestock and Poultry Multi-Omics, Ministry of Agriculture and Rural Affairs, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, China.
Xianbo JiaKey Laboratory of Livestock and Poultry Multi-Omics, Ministry of Agriculture and Rural Affairs, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, China.ORCID 0000-0002-6885-4104
Xiang GanScientific Research Center, Guilin Medical University, Guilin 541199, China.
Wenqiang SunKey Laboratory of Livestock and Poultry Multi-Omics, Ministry of Agriculture and Rural Affairs, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, China.

Funding

Guangxi Nature Science Foundation 2022GXNSFBA035582National Natural Science Foundation of China Youth Science Foundation Project 32202670Sichuan innovation team of national modern agricultural industry technology system SCCXTD-2024-13the 74th Batch of General Grants for Postdoctoral Researchers in China 2023M742516
6 · The paper itself

Abstract

Granulosa cells (GCs) are essential for follicular growth and development, and their functional state critically impacts folliculogenesis.

Indexed as

BetaineFerroptosisGranulosa CellsMetabolomicsTumor Protein p73Amino Acid Transport System y+AnimalsCattleCells, CulturedFemaleGlutathioneHydrogen PeroxideLipid PeroxidationOxidative StressAmino Acid Transport System y+BetaineGlutathioneHydrogen PeroxideTumor Protein p73betainecattleferroptosisgranulosa cellsmetabolomicsTAp73α

Identifiers

PMID40649823
PMCPMC12250254

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.