Evidence map›Paper›PMID 40650261›Full record

ArticleInternational journal of molecular sciences2025

Endothelial Protein Changes Indicative of Endometriosis in Unexplained Infertility, an Exploratory Study.

Heba Malik, Sirine Zamouri, Samir Akkawi, Siddh Mehra, Rana Mouaki, Thozhukat Sathyapalan, Manjula Nandakumar, Alexandra E Butler, Stephen L Atkin

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Heba MalikSchool of Medicine, Royal College of Surgeons in Ireland-Medical University of Bahrain, Busaiteen P.O. Box 15503, Bahrain.
Sirine ZamouriSchool of Medicine, Royal College of Surgeons in Ireland-Medical University of Bahrain, Busaiteen P.O. Box 15503, Bahrain.ORCID 0009-0004-8458-2710
Samir AkkawiSchool of Medicine, Royal College of Surgeons in Ireland-Medical University of Bahrain, Busaiteen P.O. Box 15503, Bahrain.
Siddh MehraSchool of Medicine, Royal College of Surgeons in Ireland-Medical University of Bahrain, Busaiteen P.O. Box 15503, Bahrain.
Rana MouakiSchool of Medicine, Royal College of Surgeons in Ireland-Medical University of Bahrain, Busaiteen P.O. Box 15503, Bahrain.
Thozhukat SathyapalanHull York Medical School, University of Hull, Hull HU6 7RX, UK.ORCID 0000-0003-3544-2231
Manjula NandakumarResearch Department, Royal College of Surgeons in Ireland-Medical University of Bahrain, Busaiteen P.O. Box 15503, Bahrain.
Alexandra E ButlerResearch Department, Royal College of Surgeons in Ireland-Medical University of Bahrain, Busaiteen P.O. Box 15503, Bahrain.ORCID 0000-0002-5762-3917
Stephen L AtkinResearch Department, Royal College of Surgeons in Ireland-Medical University of Bahrain, Busaiteen P.O. Box 15503, Bahrain.ORCID 0000-0002-5887-7257

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous research has linked both endothelial protein changes and vitamin D with infertility. This study was undertaken to investigate the association of proteins associated with endothelial function and vitamin D status in the luteal phase at day 21 in a group of non-obese women prior to in vitro fertilization (IVF) with either unexplained infertility (UI) or male factor infertility (MFI). Twenty-five non-obese Caucasian women from a UK academic center with MFI (

Indexed as

EndometriosisInfertility, FemaleAdultBiomarkersFemaleFertilization in VitroHumansMaleVascular Cell Adhesion Molecule-1Vascular Endothelial Growth Factor AVitamin DBiomarkersVascular Cell Adhesion Molecule-1Vascular Endothelial Growth Factor AVitamin Dangiopoietin-1endothelial cell markerssICAM-3sTie-2unexplained infertilityVCAMVEGFvitamin D

Identifiers

PMID40650261
PMCPMC12250152

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.