Evidence map›Paper›PMID 40650284›Full record

ArticleInternational journal of molecular sciences2025

Andrographolide Mitigates Inflammation and Reverses UVB-Induced Metabolic Reprogramming in HaCaT Cells.

Carolina Manosalva, Pablo Alarcón, Lucas Grassau, Carmen Cortés, Juan L Hancke, Rafael A Burgos

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Functional Characterization ofFoods (Basel, Switzerland) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Carolina ManosalvaInstitute of Pharmacy, Faculty of Sciences, Universidad Austral de Chile, Valdivia 5090000, Chile.
Pablo AlarcónLaboratory of Inflammation Pharmacology and Immunometabolism, Institute of Pharmacology and Morphophysiology, Faculty of Veterinary Sciences, Universidad Austral de Chile, Valdivia 5090000, Chile.
Lucas GrassauInstitute of Pharmacy, Faculty of Sciences, Universidad Austral de Chile, Valdivia 5090000, Chile.
Carmen CortésInstitute of Pharmacy, Faculty of Sciences, Universidad Austral de Chile, Valdivia 5090000, Chile.
Juan L HanckeLaboratory of Inflammation Pharmacology and Immunometabolism, Institute of Pharmacology and Morphophysiology, Faculty of Veterinary Sciences, Universidad Austral de Chile, Valdivia 5090000, Chile.
Rafael A BurgosLaboratory of Inflammation Pharmacology and Immunometabolism, Institute of Pharmacology and Morphophysiology, Faculty of Veterinary Sciences, Universidad Austral de Chile, Valdivia 5090000, Chile.ORCID 0000-0002-8182-2502

Funding

Fondo Nacional de Desarrollo Científico y Tecnológico 11220320Fondo Nacional de Desarrollo Científico y Tecnológico 1210754Fondo Nacional de Desarrollo Científico y Tecnológico 1250695
6 · The paper itself

Abstract

Andrographolide (AP), a bioactive compound from

Indexed as

Anti-Inflammatory AgentsDiterpenesInflammationUltraviolet RaysCell MovementHaCaT CellsHumansKeratinocytesMetabolic ReprogrammingWound HealingandrographolideAnti-Inflammatory AgentsDiterpenesandrographolidekeratinocytemetabolismphotoagingwound healing

Identifiers

PMID40650284
PMCPMC12249694

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.