Evidence map›Paper›PMID 40650288›Full record

ArticleInternational journal of molecular sciences2025

S-Nitrosylation of p53 in Melanoma Cells Under Nitrosative Stress.

Mariana Grigoruta, Li Li, Leyuan Chen, Fancui Meng, Kevin P Rosenblatt, Yiliang Li, Elizabeth A Grimm, Yong Qin

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Nitration in cancer signaling.Redox biology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mariana GrigorutaDepartment of Pharmaceutical Sciences, School of Pharmacy, The University of Texas at El Paso, El Paso, TX 79902, USA.ORCID 0000-0002-2511-0914
Li LiClinical and Translational Proteomics Service Center, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.ORCID 0000-0002-1313-3916
Leyuan ChenTianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Peking Union Medical College & Chinese Academy of Medical Sciences, Tianjin 300192, China.
Fancui MengTianjin Key Laboratory of Molecular Design and Drug Discovery, Tianjin Institute of Pharmaceutical Research, Tianjin 300301, China.
Kevin P RosenblattClinical and Translational Proteomics Service Center, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
Yiliang LiTianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Peking Union Medical College & Chinese Academy of Medical Sciences, Tianjin 300192, China.
Elizabeth A GrimmDepartment of Melanoma Medical Oncology, MD Anderson Cancer Center the University of Texas, Houston, TX 77030, USA.
Yong QinDepartment of Pharmaceutical Sciences, School of Pharmacy, The University of Texas at El Paso, El Paso, TX 79902, USA.ORCID 0000-0003-4743-938X

Funding

UT M.D. Anderson Cancer Center SPORE in MelanomaP50CA093459 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI GRIMM, ELIZABETH A · 2004 to 2014
$23.7M
NCI NIH HHS P50 CA093459The Lizanell and Colbert Coldwell Foundation Research Grant Research Fund 2023The School of Pharmacy at the University of Texas at El Paso Startup
6 · The paper itself

Abstract

Article [...].

Indexed as

MelanomaNitrosative StressTumor Suppressor Protein p53Cell Line, TumorHumansTP53 protein, humanTumor Suppressor Protein p53

Identifiers

PMID40650288
PMCPMC12250093

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.