SynthesisAnnals of medicine2025
Prognostic and clinicopathological value of fibrinogen-to-albumin ratio in colorectal cancer: a meta-analysis.
Synthesis in Annals of medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Construction of a nomogram for preoperative prediction of occult peritoneal metastasis in advanced gastric cancer based on circulating tumor cells and fibrinogen to albumin ratio.Discover oncology · 2026Article
- Immunologically-based nutritional status assessment amongst preoperative colorectal cancer patients - does it link to TNM stage.Frontiers in immunology · 2026Article
- A novel prognostic model integrating host vulnerability and tumor biology for elderly patients with diffuse large B-cell lymphoma: the BAMAL score.Frontiers in oncology · 2026Article
- Albumin and neutrophil combined prognostic grade for predicting overall survival in colorectal cancer: a retrospective cohort study.Frontiers in oncology · 2026Article
- Transcobalamin I: a potential diagnostic biomarker and therapeutic target for deep venous thrombus in colorectal cancer.Archives of medical science : AMS · 2025Article
Corrections and comments
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Authors and funding
4 authors.
Funding
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Abstract
backgroundThe fibrinogen-to-albumin ratio (FAR) has been extensively studied for its potential to predict the prognosis of patients with colorectal cancer (CRC). However, findings have been inconsistent. Therefore, this meta-analysis aims to examine the prognostic value of FAR in CRC.
methodsA comprehensive search of PubMed, Web of Science, Cochrane Library, and Embase was conducted up to January 14, 2025. Hazard ratios (HRs) and 95% confidence intervals (CIs) were calculated to assess the value of FAR for estimating overall survival (OS) and progression-free survival (PFS) in patients with CRC. Additionally, the relationship between FAR and CRC clinicopathological characteristics was explored using pooled odds ratios (ORs) with corresponding 95% CIs.
resultsThis meta-analysis included 10 studies comprising 4,704 patients. The findings indicated that elevated FAR was significantly associated with worse OS (HR = 1.59, 95% CI = 1.38-1.83,
conclusionsElevated FAR is strongly associated with poor OS and PFS in patients with CRC, as well as with older age and poor tumor differentiation, suggesting its potential as a prognostic marker.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.