Evidence map›Paper›PMID 40652049›Full record

ArticleScientific reports2025

Combination of genetic studies and animal modeling proposes TMPRSS9 as a candidate gene for serum K

Muriel Auberson, Dongmei Wang, Elodie Ehret, Tanguy Corre, Deepika Anand, Asma Mechakra, Olivier Staub, Murielle Bochud, Edith Hummler

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Muriel AubersonDepartment of Biomedical Sciences, University of Lausanne, 27 rue du Bugnon, 1011, Lausanne, Switzerland.
Dongmei WangDepartment of Biomedical Sciences, University of Lausanne, 27 rue du Bugnon, 1011, Lausanne, Switzerland.
Elodie EhretDepartment of Biomedical Sciences, University of Lausanne, 27 rue du Bugnon, 1011, Lausanne, Switzerland.
Tanguy CorreDepartment of Epidemiology and Health Systems (DESS), University Center for General Medicine and Public Health (UNISANTE), Lausanne, Switzerland.
Deepika AnandDepartment of Biomedical Sciences, University of Lausanne, 27 rue du Bugnon, 1011, Lausanne, Switzerland.
Asma MechakraDepartment of Biomedical Sciences, University of Lausanne, 27 rue du Bugnon, 1011, Lausanne, Switzerland.
Olivier StaubDepartment of Biomedical Sciences, University of Lausanne, 27 rue du Bugnon, 1011, Lausanne, Switzerland.
Murielle BochudDepartment of Epidemiology and Health Systems (DESS), University Center for General Medicine and Public Health (UNISANTE), Lausanne, Switzerland.
Edith HummlerDepartment of Biomedical Sciences, University of Lausanne, 27 rue du Bugnon, 1011, Lausanne, Switzerland. Edith.Hummler@unil.ch.

Funding

NCCR Kidney.CH N-403-07-23Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung 31003A_182478/1
6 · The paper itself

Abstract

A candidate gene association analysis identified TMPRSS9 as gene for potassium sensitivity in women. To validate this finding, constitutive and conditional Tmprss9 knockout mice were generated and subjected to dietary K

Indexed as

Membrane ProteinsPotassiumSerine EndopeptidasesAnimalsFemaleGenetic Association StudiesHumansMaleMiceMice, KnockoutProstasinSodiumMembrane ProteinsPotassiumProstasinSerine EndopeptidasesSodiumDietary potassiumNa+ handlingProteasesSex specificityVariation in K+

Identifiers

PMID40652049
PMCPMC12255782

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.