Evidence map›Paper›PMID 40652156›Full record

ArticleBiochemical genetics2026

Transcriptome Analysis Elucidates the Essential Pathways and Candidate Genes Involved in Chloroplast Development Between True Leaves and Cotyledon in Trichosanthes kirilowii Maxim.

Zhuanzhuan Jiang, Wanru Zhang, Ke Li, Xin Huang, Xiaojuan Li, Shao Yang

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Article in Biochemical genetics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Zhuanzhuan JiangKey Lab. of Biodiversity Conservation and Characteristic Resource Utilization in Southwest Anhui, Anqing, 246133, China. zzjiang@whu.edu.cn.
Wanru ZhangKey Lab. of Biodiversity Conservation and Characteristic Resource Utilization in Southwest Anhui, Anqing, 246133, China.
Ke LiKey Lab. of Biodiversity Conservation and Characteristic Resource Utilization in Southwest Anhui, Anqing, 246133, China.
Xin HuangKey Lab. of Biodiversity Conservation and Characteristic Resource Utilization in Southwest Anhui, Anqing, 246133, China.
Xiaojuan LiKey Lab. of Biodiversity Conservation and Characteristic Resource Utilization in Southwest Anhui, Anqing, 246133, China.
Shao YangKey Lab. of Biodiversity Conservation and Characteristic Resource Utilization in Southwest Anhui, Anqing, 246133, China.

Funding

the Key Laboratory of Biodiversity Conservation and Characteristic Resource Utilization in Southwest Anhui Wxn202411the Scientific Research Foundation for Higher Education Institutions in Anhui Province KJ2021A0647, 2022AH051034, 2022AH051048the State Key Laboratory of Hybrid Rice Program at Wuhan University KF202204
6 · The paper itself

Abstract

Trichosanthes kirilowii (Cucurbitaceae) is a dicotyledonous plant with morphologically and functionally distinct true leaves and cotyledons. This study integrates morphological, physiological, and transcriptomic analyses to systematically compare these two leaf types. True leaves were significantly larger, thinner, and contained higher chlorophyll a and chlorophyll b content than the smaller, thicker cotyledons. Furthermore, chloroplast thylakoid protein distribution differed between the tissues, with cotyledons enriched in low-molecular-weight chloroplast proteins. Transcriptomic profiling revealed divergent expression of genes associated with chloroplast development, including those involved in photosynthesis, pigment biosynthesis, and hormone synthesis pathways. qPCR validated key differentially expressed genes. These findings provide a comprehensive framework for understanding the molecular and functional specialization of true leaves and cotyledons in T. kirilowii, offering insights into tissue-specific chloroplast development in dicots.

Indexed as

ChloroplastsCotyledonPlant LeavesTranscriptomeTrichosanthesChlorophyllGene Expression ProfilingGene Expression Regulation, PlantPhotosynthesisPlant ProteinsChlorophyllPlant ProteinsChloroplast developmentCotyledonTrichosanthes kirilowii MaximTrue leaves

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.